| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFE94585.1 | HsrA_5 | HMPREF0758_3819 | HMPREF0758_3817 | Hypothetical protein; InterPro: IPR016181. | Transporter, major facilitator family protein; COG: COG0477; Pfam: PF07690; InterPro: IPR011701. | 0.531 |
| EFE94585.1 | mocA | HMPREF0758_3819 | HMPREF0758_3818 | Hypothetical protein; InterPro: IPR016181. | Oxidoreductase, aldo/keto reductase family protein; COG: COG0667; Pfam: PF00248; InterPro: IPR001395. | 0.532 |
| EFE94585.1 | ydfG | HMPREF0758_3819 | HMPREF0758_3820 | Hypothetical protein; InterPro: IPR016181. | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG: COG4221; Pfam: PF00106; InterPro: IPR002198; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.566 |
| HsrA_5 | EFE94585.1 | HMPREF0758_3817 | HMPREF0758_3819 | Transporter, major facilitator family protein; COG: COG0477; Pfam: PF07690; InterPro: IPR011701. | Hypothetical protein; InterPro: IPR016181. | 0.531 |
| HsrA_5 | mocA | HMPREF0758_3817 | HMPREF0758_3818 | Transporter, major facilitator family protein; COG: COG0477; Pfam: PF07690; InterPro: IPR011701. | Oxidoreductase, aldo/keto reductase family protein; COG: COG0667; Pfam: PF00248; InterPro: IPR001395. | 0.773 |
| HsrA_5 | ydfG | HMPREF0758_3817 | HMPREF0758_3820 | Transporter, major facilitator family protein; COG: COG0477; Pfam: PF07690; InterPro: IPR011701. | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG: COG4221; Pfam: PF00106; InterPro: IPR002198; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.402 |
| entF | kbl | HMPREF0758_2676 | HMPREF0758_1244 | AMP-binding enzyme; COG: COG1020; Pfam: PF00668,PF00501,PF00550,PF00975; InterPro: IPR010071. | Glycine C-acetyltransferase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | 0.416 |
| entF | ydfG | HMPREF0758_2676 | HMPREF0758_3820 | AMP-binding enzyme; COG: COG1020; Pfam: PF00668,PF00501,PF00550,PF00975; InterPro: IPR010071. | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG: COG4221; Pfam: PF00106; InterPro: IPR002198; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.535 |
| gcvP | itaE | HMPREF0758_2216 | HMPREF0758_4468 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Beta-eliminating lyase; COG: COG2008; Pfam: PF01212; InterPro: IPR001597. | 0.951 |
| gcvP | kbl | HMPREF0758_2216 | HMPREF0758_1244 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Glycine C-acetyltransferase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | 0.945 |
| gcvP | ydfG | HMPREF0758_2216 | HMPREF0758_3820 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG: COG4221; Pfam: PF00106; InterPro: IPR002198; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.452 |
| itaE | gcvP | HMPREF0758_4468 | HMPREF0758_2216 | Beta-eliminating lyase; COG: COG2008; Pfam: PF01212; InterPro: IPR001597. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.951 |
| itaE | kbl | HMPREF0758_4468 | HMPREF0758_1244 | Beta-eliminating lyase; COG: COG2008; Pfam: PF01212; InterPro: IPR001597. | Glycine C-acetyltransferase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | 0.914 |
| itaE | tdh | HMPREF0758_4468 | HMPREF0758_1243 | Beta-eliminating lyase; COG: COG2008; Pfam: PF01212; InterPro: IPR001597. | L-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. | 0.900 |
| itaE | ydfG | HMPREF0758_4468 | HMPREF0758_3820 | Beta-eliminating lyase; COG: COG2008; Pfam: PF01212; InterPro: IPR001597. | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG: COG4221; Pfam: PF00106; InterPro: IPR002198; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.903 |
| kbl | entF | HMPREF0758_1244 | HMPREF0758_2676 | Glycine C-acetyltransferase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | AMP-binding enzyme; COG: COG1020; Pfam: PF00668,PF00501,PF00550,PF00975; InterPro: IPR010071. | 0.416 |
| kbl | gcvP | HMPREF0758_1244 | HMPREF0758_2216 | Glycine C-acetyltransferase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.945 |
| kbl | itaE | HMPREF0758_1244 | HMPREF0758_4468 | Glycine C-acetyltransferase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | Beta-eliminating lyase; COG: COG2008; Pfam: PF01212; InterPro: IPR001597. | 0.914 |
| kbl | tdh | HMPREF0758_1244 | HMPREF0758_1243 | Glycine C-acetyltransferase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | L-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. | 0.996 |
| kbl | ydfG | HMPREF0758_1244 | HMPREF0758_3820 | Glycine C-acetyltransferase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG: COG4221; Pfam: PF00106; InterPro: IPR002198; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.900 |