STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
manAMannose-6-phosphate isomerase, class I; COG: COG1482; Pfam: PF01238; InterPro: IPR001250; Belongs to the mannose-6-phosphate isomerase type 1 family. (392 aa)    
Predicted Functional Partners:
pgi
Glucose-6-phosphate isomerase; COG: COG0166; Pfam: PF00342; InterPro: IPR001672; Belongs to the GPI family.
 
 
 0.950
manX
PTS system, mannose/fructose/sorbose family, IIB component; COG: COG3444; Pfam: PF03610,PF03830; InterPro: IPR004720.
    
 0.947
nagB
Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
     
 0.928
manB
Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; COG: COG1109; Pfam: PF02878,PF02879,PF02880,PF00408; InterPro: IPR016055.
  
 
 0.924
mak
ROK family protein; COG: COG1940; Pfam: PF00480; InterPro: IPR000600.
  
 
 0.918
glmS
Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
  
 
 0.918
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
    
 0.914
PfkA_2
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family.
    
 0.914
mtlD
Mannitol dehydrogenase domain protein; COG: COG0246; Pfam: PF01232,PF08125; InterPro: IPR013118.
    
 0.912
fbp
Fructose-1,6-bisphosphatase; COG: COG0158; Pfam: PF00316; InterPro: IPR000146; Belongs to the FBPase class 1 family.
     
 0.910
Your Current Organism:
Serratia odorifera
NCBI taxonomy Id: 667129
Other names: S. odorifera DSM 4582, Serratia odorifera DSM 4582, Serratia odorifera str. DSM 4582, Serratia odorifera strain DSM 4582
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