| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFE94324.1 | pdxY | HMPREF0758_3898 | HMPREF0758_3897 | Hypothetical protein. | Pyridoxal kinase; Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP. | 0.425 |
| EFE95393.1 | pdxJ | HMPREF0758_3084 | HMPREF0758_2458 | Pyridoxamine 5'-phosphate oxidase family protein; COG: COG3576; Pfam: PF01243; InterPro: IPR011576. | Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.499 |
| EFE95393.1 | pdxK | HMPREF0758_3084 | HMPREF0758_3651 | Pyridoxamine 5'-phosphate oxidase family protein; COG: COG3576; Pfam: PF01243; InterPro: IPR011576. | Pyridoxal kinase; COG: COG2240; Pfam: PF00294; InterPro: IPR004625; Belongs to the pyridoxine kinase family. | 0.499 |
| EFE95393.1 | pdxY | HMPREF0758_3084 | HMPREF0758_3897 | Pyridoxamine 5'-phosphate oxidase family protein; COG: COG3576; Pfam: PF01243; InterPro: IPR011576. | Pyridoxal kinase; Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP. | 0.567 |
| YdbC_2 | fabG13 | HMPREF0758_2938 | HMPREF0758_2980 | Oxidoreductase, aldo/keto reductase family protein; COG: COG0667; Pfam: PF00248; InterPro: IPR001395. | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG: COG1028; Pfam: PF00106; InterPro: IPR016040. | 0.900 |
| YdbC_2 | pdxH | HMPREF0758_2938 | HMPREF0758_3900 | Oxidoreductase, aldo/keto reductase family protein; COG: COG0667; Pfam: PF00248; InterPro: IPR001395. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.900 |
| YdbC_2 | pdxK | HMPREF0758_2938 | HMPREF0758_3651 | Oxidoreductase, aldo/keto reductase family protein; COG: COG0667; Pfam: PF00248; InterPro: IPR001395. | Pyridoxal kinase; COG: COG2240; Pfam: PF00294; InterPro: IPR004625; Belongs to the pyridoxine kinase family. | 0.900 |
| YdbC_2 | pdxY | HMPREF0758_2938 | HMPREF0758_3897 | Oxidoreductase, aldo/keto reductase family protein; COG: COG0667; Pfam: PF00248; InterPro: IPR001395. | Pyridoxal kinase; Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP. | 0.900 |
| YdcR_4 | pdxK | HMPREF0758_3654 | HMPREF0758_3651 | Transcriptional regulator, GntR family; Pfam: PF00392,PF00155; InterPro: IPR015421. | Pyridoxal kinase; COG: COG2240; Pfam: PF00294; InterPro: IPR004625; Belongs to the pyridoxine kinase family. | 0.734 |
| YdcR_4 | pdxY | HMPREF0758_3654 | HMPREF0758_3897 | Transcriptional regulator, GntR family; Pfam: PF00392,PF00155; InterPro: IPR015421. | Pyridoxal kinase; Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP. | 0.426 |
| fabG13 | YdbC_2 | HMPREF0758_2980 | HMPREF0758_2938 | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG: COG1028; Pfam: PF00106; InterPro: IPR016040. | Oxidoreductase, aldo/keto reductase family protein; COG: COG0667; Pfam: PF00248; InterPro: IPR001395. | 0.900 |
| fabG13 | pdxH | HMPREF0758_2980 | HMPREF0758_3900 | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG: COG1028; Pfam: PF00106; InterPro: IPR016040. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.900 |
| fabG13 | pdxK | HMPREF0758_2980 | HMPREF0758_3651 | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG: COG1028; Pfam: PF00106; InterPro: IPR016040. | Pyridoxal kinase; COG: COG2240; Pfam: PF00294; InterPro: IPR004625; Belongs to the pyridoxine kinase family. | 0.903 |
| fabG13 | pdxY | HMPREF0758_2980 | HMPREF0758_3897 | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG: COG1028; Pfam: PF00106; InterPro: IPR016040. | Pyridoxal kinase; Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP. | 0.903 |
| fkuA | pdxK | HMPREF0758_2116 | HMPREF0758_3651 | Pyridoxal phosphate enzyme, YggS family; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | Pyridoxal kinase; COG: COG2240; Pfam: PF00294; InterPro: IPR004625; Belongs to the pyridoxine kinase family. | 0.499 |
| fkuA | pdxY | HMPREF0758_2116 | HMPREF0758_3897 | Pyridoxal phosphate enzyme, YggS family; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. | Pyridoxal kinase; Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP. | 0.499 |
| pdxH | YdbC_2 | HMPREF0758_3900 | HMPREF0758_2938 | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | Oxidoreductase, aldo/keto reductase family protein; COG: COG0667; Pfam: PF00248; InterPro: IPR001395. | 0.900 |
| pdxH | fabG13 | HMPREF0758_3900 | HMPREF0758_2980 | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG: COG1028; Pfam: PF00106; InterPro: IPR016040. | 0.900 |
| pdxH | pdxJ | HMPREF0758_3900 | HMPREF0758_2458 | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.934 |
| pdxH | pdxK | HMPREF0758_3900 | HMPREF0758_3651 | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | Pyridoxal kinase; COG: COG2240; Pfam: PF00294; InterPro: IPR004625; Belongs to the pyridoxine kinase family. | 0.918 |