| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFE94329.1 | MliC | HMPREF0758_3903 | HMPREF0758_3901 | Hypothetical protein. | Putative Membrane-bound lysozyme inhibitor of C-type lysozyme; COG: COG3895. | 0.615 |
| EFE94329.1 | anmK | HMPREF0758_3903 | HMPREF0758_3902 | Hypothetical protein. | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.757 |
| EFE94329.1 | pdxH | HMPREF0758_3903 | HMPREF0758_3900 | Hypothetical protein. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.552 |
| MliC | EFE94329.1 | HMPREF0758_3901 | HMPREF0758_3903 | Putative Membrane-bound lysozyme inhibitor of C-type lysozyme; COG: COG3895. | Hypothetical protein. | 0.615 |
| MliC | anmK | HMPREF0758_3901 | HMPREF0758_3902 | Putative Membrane-bound lysozyme inhibitor of C-type lysozyme; COG: COG3895. | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.655 |
| MliC | pdxH | HMPREF0758_3901 | HMPREF0758_3900 | Putative Membrane-bound lysozyme inhibitor of C-type lysozyme; COG: COG3895. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.704 |
| MliC | tyrS | HMPREF0758_3901 | HMPREF0758_3899 | Putative Membrane-bound lysozyme inhibitor of C-type lysozyme; COG: COG3895. | tyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. | 0.406 |
| YdbC_2 | fabG13 | HMPREF0758_2938 | HMPREF0758_2980 | Oxidoreductase, aldo/keto reductase family protein; COG: COG0667; Pfam: PF00248; InterPro: IPR001395. | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG: COG1028; Pfam: PF00106; InterPro: IPR016040. | 0.900 |
| YdbC_2 | pdxH | HMPREF0758_2938 | HMPREF0758_3900 | Oxidoreductase, aldo/keto reductase family protein; COG: COG0667; Pfam: PF00248; InterPro: IPR001395. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.900 |
| YdbC_2 | pdxK | HMPREF0758_2938 | HMPREF0758_3651 | Oxidoreductase, aldo/keto reductase family protein; COG: COG0667; Pfam: PF00248; InterPro: IPR001395. | Pyridoxal kinase; COG: COG2240; Pfam: PF00294; InterPro: IPR004625; Belongs to the pyridoxine kinase family. | 0.900 |
| YdbC_2 | pdxY | HMPREF0758_2938 | HMPREF0758_3897 | Oxidoreductase, aldo/keto reductase family protein; COG: COG0667; Pfam: PF00248; InterPro: IPR001395. | Pyridoxal kinase; Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP. | 0.900 |
| anmK | EFE94329.1 | HMPREF0758_3902 | HMPREF0758_3903 | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Hypothetical protein. | 0.757 |
| anmK | MliC | HMPREF0758_3902 | HMPREF0758_3901 | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Putative Membrane-bound lysozyme inhibitor of C-type lysozyme; COG: COG3895. | 0.655 |
| anmK | gcvP | HMPREF0758_3902 | HMPREF0758_2216 | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.414 |
| anmK | pdxH | HMPREF0758_3902 | HMPREF0758_3900 | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.579 |
| fabG13 | YdbC_2 | HMPREF0758_2980 | HMPREF0758_2938 | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG: COG1028; Pfam: PF00106; InterPro: IPR016040. | Oxidoreductase, aldo/keto reductase family protein; COG: COG0667; Pfam: PF00248; InterPro: IPR001395. | 0.900 |
| fabG13 | pdxH | HMPREF0758_2980 | HMPREF0758_3900 | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG: COG1028; Pfam: PF00106; InterPro: IPR016040. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.900 |
| fabG13 | pdxK | HMPREF0758_2980 | HMPREF0758_3651 | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG: COG1028; Pfam: PF00106; InterPro: IPR016040. | Pyridoxal kinase; COG: COG2240; Pfam: PF00294; InterPro: IPR004625; Belongs to the pyridoxine kinase family. | 0.903 |
| fabG13 | pdxY | HMPREF0758_2980 | HMPREF0758_3897 | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG: COG1028; Pfam: PF00106; InterPro: IPR016040. | Pyridoxal kinase; Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP. | 0.903 |
| gcvP | anmK | HMPREF0758_2216 | HMPREF0758_3902 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.414 |