| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFE94329.1 | MliC | HMPREF0758_3903 | HMPREF0758_3901 | Hypothetical protein. | Putative Membrane-bound lysozyme inhibitor of C-type lysozyme; COG: COG3895. | 0.615 |
| EFE94329.1 | anmK | HMPREF0758_3903 | HMPREF0758_3902 | Hypothetical protein. | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.757 |
| EFE94329.1 | pcp | HMPREF0758_3903 | HMPREF0758_3904 | Hypothetical protein. | Outer membrane lipoprotein pcp; COG: COG3133; Pfam: PF05433; InterPro: IPR008816. | 0.493 |
| EFE94329.1 | pdxH | HMPREF0758_3903 | HMPREF0758_3900 | Hypothetical protein. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.552 |
| EFE95828.1 | anmK | HMPREF0758_2464 | HMPREF0758_3902 | Hypothetical protein; COG: COG2103; overlaps another CDS with the same product name; 4.2.-.-. | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.580 |
| EFE95828.1 | murQ | HMPREF0758_2464 | HMPREF0758_2463 | Hypothetical protein; COG: COG2103; overlaps another CDS with the same product name; 4.2.-.-. | Putative N-acetylmuramic acid 6-phosphate etherase; COG: COG2103; Pfam: PF01380; overlaps another CDS with the same product name. | 0.980 |
| MliC | EFE94329.1 | HMPREF0758_3901 | HMPREF0758_3903 | Putative Membrane-bound lysozyme inhibitor of C-type lysozyme; COG: COG3895. | Hypothetical protein. | 0.615 |
| MliC | anmK | HMPREF0758_3901 | HMPREF0758_3902 | Putative Membrane-bound lysozyme inhibitor of C-type lysozyme; COG: COG3895. | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.655 |
| MliC | pcp | HMPREF0758_3901 | HMPREF0758_3904 | Putative Membrane-bound lysozyme inhibitor of C-type lysozyme; COG: COG3895. | Outer membrane lipoprotein pcp; COG: COG3133; Pfam: PF05433; InterPro: IPR008816. | 0.429 |
| MliC | pdxH | HMPREF0758_3901 | HMPREF0758_3900 | Putative Membrane-bound lysozyme inhibitor of C-type lysozyme; COG: COG3895. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.704 |
| ampG | anmK | HMPREF0758_0205 | HMPREF0758_3902 | Muropeptide transporter; COG: COG0477; Pfam: PF07690; InterPro: IPR011701. | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.480 |
| ampG | nagZ | HMPREF0758_0205 | HMPREF0758_4172 | Muropeptide transporter; COG: COG0477; Pfam: PF07690; InterPro: IPR011701. | Glycosyl hydrolase family 3 N-terminal domain protein; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.559 |
| anmK | EFE94329.1 | HMPREF0758_3902 | HMPREF0758_3903 | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Hypothetical protein. | 0.757 |
| anmK | EFE95828.1 | HMPREF0758_3902 | HMPREF0758_2464 | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Hypothetical protein; COG: COG2103; overlaps another CDS with the same product name; 4.2.-.-. | 0.580 |
| anmK | MliC | HMPREF0758_3902 | HMPREF0758_3901 | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Putative Membrane-bound lysozyme inhibitor of C-type lysozyme; COG: COG3895. | 0.655 |
| anmK | ampG | HMPREF0758_3902 | HMPREF0758_0205 | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Muropeptide transporter; COG: COG0477; Pfam: PF07690; InterPro: IPR011701. | 0.480 |
| anmK | murQ | HMPREF0758_3902 | HMPREF0758_2463 | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Putative N-acetylmuramic acid 6-phosphate etherase; COG: COG2103; Pfam: PF01380; overlaps another CDS with the same product name. | 0.958 |
| anmK | nagZ | HMPREF0758_3902 | HMPREF0758_4172 | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Glycosyl hydrolase family 3 N-terminal domain protein; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.639 |
| anmK | pcp | HMPREF0758_3902 | HMPREF0758_3904 | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Outer membrane lipoprotein pcp; COG: COG3133; Pfam: PF05433; InterPro: IPR008816. | 0.483 |
| anmK | pdxH | HMPREF0758_3902 | HMPREF0758_3900 | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.579 |