STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
sufEFe-S metabolism associated domain protein; Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L- alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process; Belongs to the SufE family. (138 aa)    
Predicted Functional Partners:
csdB
Bifunctional cysteine desulfurase/selenocysteine lyase; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L- selenocysteine. Selenocysteine lyase activity is however unsure in vivo.
 
 0.947
sufB
FeS assembly protein SufB; COG: COG0719; Pfam: PF01458; InterPro: IPR010231.
 
 
 0.913
sufD
FeS assembly protein SufD; COG: COG0719; Pfam: PF01458; InterPro: IPR011542.
 
 
 0.912
sufC
FeS assembly ATPase SufC; COG: COG0396; Pfam: PF00005; InterPro: IPR010230.
 
 
 0.912
csdA
Cysteine desulfurase, catalytic subunit CsdA; COG: COG0520; Pfam: PF00266; InterPro: IPR000192.
 
 0.868
sufA
FeS assembly scaffold SufA; COG: COG0316; Pfam: PF01521; InterPro: IPR000361; Belongs to the HesB/IscA family.
  
  
 0.625
ycfS
ErfK/YbiS/YcfS/YnhG; COG: COG1376; Pfam: PF01476,PF03734; InterPro: IPR005490.
       0.433
Your Current Organism:
Serratia odorifera
NCBI taxonomy Id: 667129
Other names: S. odorifera DSM 4582, Serratia odorifera DSM 4582, Serratia odorifera str. DSM 4582, Serratia odorifera strain DSM 4582
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