STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sufDFeS assembly protein SufD; COG: COG0719; Pfam: PF01458; InterPro: IPR011542. (428 aa)    
Predicted Functional Partners:
sufC
FeS assembly ATPase SufC; COG: COG0396; Pfam: PF00005; InterPro: IPR010230.
 
 
 0.999
sufB
FeS assembly protein SufB; COG: COG0719; Pfam: PF01458; InterPro: IPR010231.
 
 
0.996
csdB
Bifunctional cysteine desulfurase/selenocysteine lyase; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L- selenocysteine. Selenocysteine lyase activity is however unsure in vivo.
 
 
 0.984
csdA
Cysteine desulfurase, catalytic subunit CsdA; COG: COG0520; Pfam: PF00266; InterPro: IPR000192.
 
 
 0.930
sufE
Fe-S metabolism associated domain protein; Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L- alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process; Belongs to the SufE family.
 
 
 0.912
sufA
FeS assembly scaffold SufA; COG: COG0316; Pfam: PF01521; InterPro: IPR000361; Belongs to the HesB/IscA family.
 
 
 0.858
iscU
FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
  
  
 0.794
yhgI
IscR-regulated protein YhgI; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
 
 0.692
csdE
Cysteine desulfurase, sulfur acceptor subunit CsdE; COG: COG2166; Pfam: PF02657; InterPro: IPR003808.
 
 
 0.659
erpA
Iron-sulfur cluster assembly accessory protein; Required for insertion of 4Fe-4S clusters for at least IspG.
 
 
 0.598
Your Current Organism:
Serratia odorifera
NCBI taxonomy Id: 667129
Other names: S. odorifera DSM 4582, Serratia odorifera DSM 4582, Serratia odorifera str. DSM 4582, Serratia odorifera strain DSM 4582
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