node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EFE94396.1 | arnA | HMPREF0758_3970 | HMPREF0758_3969 | Bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; COG: COG0223; Pfam: PF00551; InterPro: IPR002376; overlaps another CDS with the same product name. | Polymyxin resistance protein PmrI; COG: COG0451; Pfam: PF02911,PF01370; InterPro: IPR016040; overlaps another CDS with the same product name. | 0.994 |
EFE94396.1 | arnB | HMPREF0758_3970 | HMPREF0758_3972 | Bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; COG: COG0223; Pfam: PF00551; InterPro: IPR002376; overlaps another CDS with the same product name. | DegT/DnrJ/EryC1/StrS aminotransferase family protein; Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily. | 0.941 |
EFE94396.1 | arnC | HMPREF0758_3970 | HMPREF0758_3971 | Bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; COG: COG0223; Pfam: PF00551; InterPro: IPR002376; overlaps another CDS with the same product name. | Glycosyltransferase, group 2 family protein; Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. | 0.948 |
EFE94396.1 | arnE | HMPREF0758_3970 | HMPREF0758_3966 | Bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; COG: COG0223; Pfam: PF00551; InterPro: IPR002376; overlaps another CDS with the same product name. | Hypothetical protein; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane; Belongs to the ArnE family. | 0.947 |
EFE94396.1 | arnF | HMPREF0758_3970 | HMPREF0758_3965 | Bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; COG: COG0223; Pfam: PF00551; InterPro: IPR002376; overlaps another CDS with the same product name. | Hypothetical protein; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane; Belongs to the ArnF family. | 0.913 |
EFE94396.1 | arnT | HMPREF0758_3970 | HMPREF0758_3967 | Bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; COG: COG0223; Pfam: PF00551; InterPro: IPR002376; overlaps another CDS with the same product name. | Dolichyl-phosphate-mannose-protein mannosyltransferase; Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. Belongs to the glycosyltransferase 83 family. | 0.980 |
EFE94396.1 | nlpC | HMPREF0758_3970 | HMPREF0758_3964 | Bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; COG: COG0223; Pfam: PF00551; InterPro: IPR002376; overlaps another CDS with the same product name. | NlpC/P60 family protein; COG: COG0791; Pfam: PF00877; InterPro: IPR000064. | 0.517 |
EFE94396.1 | pbgP | HMPREF0758_3970 | HMPREF0758_3968 | Bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; COG: COG0223; Pfam: PF00551; InterPro: IPR002376; overlaps another CDS with the same product name. | Polysaccharide deacetylase; Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily. | 0.986 |
EFE94396.1 | wbaP | HMPREF0758_3970 | HMPREF0758_3603 | Bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; COG: COG0223; Pfam: PF00551; InterPro: IPR002376; overlaps another CDS with the same product name. | Undecaprenyl-phosphate galactose phosphotransferase, WbaP; COG: COG2148; Pfam: PF02397; InterPro: IPR003362. | 0.651 |
EFE94396.1 | wecE | HMPREF0758_3970 | HMPREF0758_1517 | Bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; COG: COG0223; Pfam: PF00551; InterPro: IPR002376; overlaps another CDS with the same product name. | dTDP-4-amino-4,6-dideoxy-D-glucose transaminase; Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D- galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D- Glc4O) and L-glutamate; Belongs to the DegT/DnrJ/EryC1 family. | 0.687 |
arnA | EFE94396.1 | HMPREF0758_3969 | HMPREF0758_3970 | Polymyxin resistance protein PmrI; COG: COG0451; Pfam: PF02911,PF01370; InterPro: IPR016040; overlaps another CDS with the same product name. | Bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; COG: COG0223; Pfam: PF00551; InterPro: IPR002376; overlaps another CDS with the same product name. | 0.994 |
arnA | arnB | HMPREF0758_3969 | HMPREF0758_3972 | Polymyxin resistance protein PmrI; COG: COG0451; Pfam: PF02911,PF01370; InterPro: IPR016040; overlaps another CDS with the same product name. | DegT/DnrJ/EryC1/StrS aminotransferase family protein; Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily. | 0.994 |
arnA | arnC | HMPREF0758_3969 | HMPREF0758_3971 | Polymyxin resistance protein PmrI; COG: COG0451; Pfam: PF02911,PF01370; InterPro: IPR016040; overlaps another CDS with the same product name. | Glycosyltransferase, group 2 family protein; Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. | 0.994 |
arnA | arnE | HMPREF0758_3969 | HMPREF0758_3966 | Polymyxin resistance protein PmrI; COG: COG0451; Pfam: PF02911,PF01370; InterPro: IPR016040; overlaps another CDS with the same product name. | Hypothetical protein; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane; Belongs to the ArnE family. | 0.929 |
arnA | arnF | HMPREF0758_3969 | HMPREF0758_3965 | Polymyxin resistance protein PmrI; COG: COG0451; Pfam: PF02911,PF01370; InterPro: IPR016040; overlaps another CDS with the same product name. | Hypothetical protein; Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane; Belongs to the ArnF family. | 0.932 |
arnA | arnT | HMPREF0758_3969 | HMPREF0758_3967 | Polymyxin resistance protein PmrI; COG: COG0451; Pfam: PF02911,PF01370; InterPro: IPR016040; overlaps another CDS with the same product name. | Dolichyl-phosphate-mannose-protein mannosyltransferase; Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. Belongs to the glycosyltransferase 83 family. | 0.974 |
arnA | nlpC | HMPREF0758_3969 | HMPREF0758_3964 | Polymyxin resistance protein PmrI; COG: COG0451; Pfam: PF02911,PF01370; InterPro: IPR016040; overlaps another CDS with the same product name. | NlpC/P60 family protein; COG: COG0791; Pfam: PF00877; InterPro: IPR000064. | 0.517 |
arnA | pbgP | HMPREF0758_3969 | HMPREF0758_3968 | Polymyxin resistance protein PmrI; COG: COG0451; Pfam: PF02911,PF01370; InterPro: IPR016040; overlaps another CDS with the same product name. | Polysaccharide deacetylase; Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily. | 0.965 |
arnA | wbaP | HMPREF0758_3969 | HMPREF0758_3603 | Polymyxin resistance protein PmrI; COG: COG0451; Pfam: PF02911,PF01370; InterPro: IPR016040; overlaps another CDS with the same product name. | Undecaprenyl-phosphate galactose phosphotransferase, WbaP; COG: COG2148; Pfam: PF02397; InterPro: IPR003362. | 0.651 |
arnA | wecE | HMPREF0758_3969 | HMPREF0758_1517 | Polymyxin resistance protein PmrI; COG: COG0451; Pfam: PF02911,PF01370; InterPro: IPR016040; overlaps another CDS with the same product name. | dTDP-4-amino-4,6-dideoxy-D-glucose transaminase; Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D- galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D- Glc4O) and L-glutamate; Belongs to the DegT/DnrJ/EryC1 family. | 0.657 |