| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFE94723.1 | EFE95320.1 | HMPREF0758_3594 | HMPREF0758_3011 | Peroxidase-like protein; COG: COG4950; InterPro: IPR010195. | Alkylhydroperoxidase domain protein, Avi_7169 family; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | 0.420 |
| EFE94723.1 | cysC | HMPREF0758_3594 | HMPREF0758_0445 | Peroxidase-like protein; COG: COG4950; InterPro: IPR010195. | Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.655 |
| EFE94723.1 | cysD | HMPREF0758_3594 | HMPREF0758_0447 | Peroxidase-like protein; COG: COG4950; InterPro: IPR010195. | Sulfate adenylyltransferase, small subunit; COG: COG0175; Pfam: PF01507; InterPro: IPR011784. | 0.647 |
| EFE94723.1 | cysH | HMPREF0758_3594 | HMPREF0758_0450 | Peroxidase-like protein; COG: COG4950; InterPro: IPR010195. | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. | 0.524 |
| EFE94723.1 | cysI | HMPREF0758_3594 | HMPREF0758_0451 | Peroxidase-like protein; COG: COG4950; InterPro: IPR010195. | Sulfite reductase (NADPH) hemoprotein, beta-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.808 |
| EFE94723.1 | cysJ | HMPREF0758_3594 | HMPREF0758_0452 | Peroxidase-like protein; COG: COG4950; InterPro: IPR010195. | Sulfite reductase (NADPH) flavoprotein, alpha-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the N-terminal section; belongs to the flavodoxin family. | 0.927 |
| EFE94723.1 | cysN | HMPREF0758_3594 | HMPREF0758_0446 | Peroxidase-like protein; COG: COG4950; InterPro: IPR010195. | Sulfate adenylyltransferase, large subunit; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.799 |
| EFE94723.1 | cysP | HMPREF0758_3594 | HMPREF0758_2649 | Peroxidase-like protein; COG: COG4950; InterPro: IPR010195. | Sulfate ABC transporter, sulfate-binding protein; COG: COG4150; Pfam: PF01547; InterPro: IPR005669. | 0.931 |
| EFE94723.1 | gltP | HMPREF0758_3594 | HMPREF0758_4007 | Peroxidase-like protein; COG: COG4950; InterPro: IPR010195. | Transporter, dicarboxylate/amino acid:cation Na+/H+ symporter family protein; COG: COG1823; Pfam: PF00375; InterPro: IPR001991; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. | 0.539 |
| EFE95320.1 | EFE94723.1 | HMPREF0758_3011 | HMPREF0758_3594 | Alkylhydroperoxidase domain protein, Avi_7169 family; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | Peroxidase-like protein; COG: COG4950; InterPro: IPR010195. | 0.420 |
| EFE95320.1 | cysC | HMPREF0758_3011 | HMPREF0758_0445 | Alkylhydroperoxidase domain protein, Avi_7169 family; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.655 |
| EFE95320.1 | cysI | HMPREF0758_3011 | HMPREF0758_0451 | Alkylhydroperoxidase domain protein, Avi_7169 family; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | Sulfite reductase (NADPH) hemoprotein, beta-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.808 |
| EFE95320.1 | cysJ | HMPREF0758_3011 | HMPREF0758_0452 | Alkylhydroperoxidase domain protein, Avi_7169 family; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | Sulfite reductase (NADPH) flavoprotein, alpha-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the N-terminal section; belongs to the flavodoxin family. | 0.927 |
| EFE95320.1 | cysN | HMPREF0758_3011 | HMPREF0758_0446 | Alkylhydroperoxidase domain protein, Avi_7169 family; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | Sulfate adenylyltransferase, large subunit; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.799 |
| EFE95320.1 | cysP | HMPREF0758_3011 | HMPREF0758_2649 | Alkylhydroperoxidase domain protein, Avi_7169 family; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | Sulfate ABC transporter, sulfate-binding protein; COG: COG4150; Pfam: PF01547; InterPro: IPR005669. | 0.931 |
| EFE95320.1 | gltP | HMPREF0758_3011 | HMPREF0758_4007 | Alkylhydroperoxidase domain protein, Avi_7169 family; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | Transporter, dicarboxylate/amino acid:cation Na+/H+ symporter family protein; COG: COG1823; Pfam: PF00375; InterPro: IPR001991; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. | 0.539 |
| YdjM | gltP | HMPREF0758_4006 | HMPREF0758_4007 | Putative membrane-bound metal-dependent hydrolase; COG: COG1988; Pfam: PF04307; InterPro: IPR007404. | Transporter, dicarboxylate/amino acid:cation Na+/H+ symporter family protein; COG: COG1823; Pfam: PF00375; InterPro: IPR001991; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. | 0.569 |
| cysC | EFE94723.1 | HMPREF0758_0445 | HMPREF0758_3594 | Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. | Peroxidase-like protein; COG: COG4950; InterPro: IPR010195. | 0.655 |
| cysC | EFE95320.1 | HMPREF0758_0445 | HMPREF0758_3011 | Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. | Alkylhydroperoxidase domain protein, Avi_7169 family; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. | 0.655 |
| cysC | cysD | HMPREF0758_0445 | HMPREF0758_0447 | Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. | Sulfate adenylyltransferase, small subunit; COG: COG0175; Pfam: PF01507; InterPro: IPR011784. | 0.999 |