| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFE94396.1 | arnA | HMPREF0758_3970 | HMPREF0758_3969 | Bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; COG: COG0223; Pfam: PF00551; InterPro: IPR002376; overlaps another CDS with the same product name. | Polymyxin resistance protein PmrI; COG: COG0451; Pfam: PF02911,PF01370; InterPro: IPR016040; overlaps another CDS with the same product name. | 0.994 |
| EFE94396.1 | rlmN | HMPREF0758_3970 | HMPREF0758_2498 | Bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; COG: COG0223; Pfam: PF00551; InterPro: IPR002376; overlaps another CDS with the same product name. | 23S rRNA m2A2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 0.408 |
| EFE94396.1 | rplW | HMPREF0758_3970 | HMPREF0758_0959 | Bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; COG: COG0223; Pfam: PF00551; InterPro: IPR002376; overlaps another CDS with the same product name. | Ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. | 0.482 |
| EFE94396.1 | rpmD | HMPREF0758_3970 | HMPREF0758_0943 | Bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; COG: COG0223; Pfam: PF00551; InterPro: IPR002376; overlaps another CDS with the same product name. | Ribosomal protein L30; COG: COG1841; Pfam: PF00327; InterPro: IPR005996. | 0.511 |
| EFE94396.1 | rsmF | HMPREF0758_3970 | HMPREF0758_4017 | Bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; COG: COG0223; Pfam: PF00551; InterPro: IPR002376; overlaps another CDS with the same product name. | NOL1/NOP2/sun family protein; Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA. | 0.665 |
| arnA | EFE94396.1 | HMPREF0758_3969 | HMPREF0758_3970 | Polymyxin resistance protein PmrI; COG: COG0451; Pfam: PF02911,PF01370; InterPro: IPR016040; overlaps another CDS with the same product name. | Bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; COG: COG0223; Pfam: PF00551; InterPro: IPR002376; overlaps another CDS with the same product name. | 0.994 |
| arnA | rlmN | HMPREF0758_3969 | HMPREF0758_2498 | Polymyxin resistance protein PmrI; COG: COG0451; Pfam: PF02911,PF01370; InterPro: IPR016040; overlaps another CDS with the same product name. | 23S rRNA m2A2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 0.408 |
| arnA | rplW | HMPREF0758_3969 | HMPREF0758_0959 | Polymyxin resistance protein PmrI; COG: COG0451; Pfam: PF02911,PF01370; InterPro: IPR016040; overlaps another CDS with the same product name. | Ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. | 0.482 |
| arnA | rpmD | HMPREF0758_3969 | HMPREF0758_0943 | Polymyxin resistance protein PmrI; COG: COG0451; Pfam: PF02911,PF01370; InterPro: IPR016040; overlaps another CDS with the same product name. | Ribosomal protein L30; COG: COG1841; Pfam: PF00327; InterPro: IPR005996. | 0.511 |
| arnA | rsmF | HMPREF0758_3969 | HMPREF0758_4017 | Polymyxin resistance protein PmrI; COG: COG0451; Pfam: PF02911,PF01370; InterPro: IPR016040; overlaps another CDS with the same product name. | NOL1/NOP2/sun family protein; Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA. | 0.665 |
| pqiA | rsmF | HMPREF0758_4015 | HMPREF0758_4017 | Integral membrane protein, PqiA family; COG: COG2995; Pfam: PF04403; InterPro: IPR007498. | NOL1/NOP2/sun family protein; Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA. | 0.653 |
| prmA | rsmF | HMPREF0758_1805 | HMPREF0758_4017 | Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. | NOL1/NOP2/sun family protein; Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA. | 0.660 |
| rlmN | EFE94396.1 | HMPREF0758_2498 | HMPREF0758_3970 | 23S rRNA m2A2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | Bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; COG: COG0223; Pfam: PF00551; InterPro: IPR002376; overlaps another CDS with the same product name. | 0.408 |
| rlmN | arnA | HMPREF0758_2498 | HMPREF0758_3969 | 23S rRNA m2A2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | Polymyxin resistance protein PmrI; COG: COG0451; Pfam: PF02911,PF01370; InterPro: IPR016040; overlaps another CDS with the same product name. | 0.408 |
| rlmN | rsmF | HMPREF0758_2498 | HMPREF0758_4017 | 23S rRNA m2A2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | NOL1/NOP2/sun family protein; Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA. | 0.722 |
| rlmN | thiI | HMPREF0758_2498 | HMPREF0758_0218 | 23S rRNA m2A2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.454 |
| rplJ | rplW | HMPREF0758_1660 | HMPREF0758_0959 | Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | Ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. | 0.998 |
| rplJ | rpmD | HMPREF0758_1660 | HMPREF0758_0943 | Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | Ribosomal protein L30; COG: COG1841; Pfam: PF00327; InterPro: IPR005996. | 0.998 |
| rplJ | rrmJ | HMPREF0758_1660 | HMPREF0758_0811 | Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | Ribosomal RNA large subunit methyltransferase J; COG: COG0293; Pfam: PF01728; InterPro: IPR002877. | 0.764 |
| rplJ | rsmF | HMPREF0758_1660 | HMPREF0758_4017 | Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. | NOL1/NOP2/sun family protein; Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA. | 0.731 |