STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pheA2Putative chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. (176 aa)    
Predicted Functional Partners:
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
  
 
 0.958
trpG2
Glutamine amidotransferase, class I; COG: COG0512; Pfam: PF00117; InterPro: IPR006221.
  
 
 0.948
tyrA
Chorismate mutase; COG: COG0287; Pfam: PF01817,PF02153; InterPro: IPR003099.
  
 0.935
pheA
Chorismate mutase; COG: COG0077; Pfam: PF01817,PF00800; InterPro: IPR001086.
  
 
 0.919
pheC
ABC transporter, substrate-binding protein, family 3; COG: COG0834; Pfam: PF00497; InterPro: IPR001638.
  
 
 0.914
trpE
Anthranilate synthase component I; COG: COG0147; Pfam: PF04715,PF00425; InterPro: IPR005801.
  
 
 0.913
tyrB
Aminotransferase, class I/II; COG: COG1448; Pfam: PF00155; InterPro: IPR000796.
    
 0.912
entC
Isochorismate synthase; COG: COG1169; Pfam: PF00425; InterPro: IPR004561.
 
 
 0.888
menF
Isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate.
  
 
 0.850
pabB
Aminodeoxychorismate synthase, component I; COG: COG0147; Pfam: PF04715,PF00425; InterPro: IPR005801.
  
 
 0.826
Your Current Organism:
Serratia odorifera
NCBI taxonomy Id: 667129
Other names: S. odorifera DSM 4582, Serratia odorifera DSM 4582, Serratia odorifera str. DSM 4582, Serratia odorifera strain DSM 4582
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