| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFE94900.1 | EFE96731.1 | HMPREF0758_3334 | HMPREF0758_1590 | Hypothetical protein; COG: COG3140; Pfam: PF03701; InterPro: IPR005371; Belongs to the UPF0181 family. | Hypothetical protein; COG: COG3776; Pfam: PF06611; InterPro: IPR009525. | 0.773 |
| EFE94900.1 | LpoB | HMPREF0758_3334 | HMPREF0758_4174 | Hypothetical protein; COG: COG3140; Pfam: PF03701; InterPro: IPR005371; Belongs to the UPF0181 family. | Hypothetical protein; COG: COG3417. | 0.491 |
| EFE94900.1 | pqqL | HMPREF0758_3334 | HMPREF0758_1502 | Hypothetical protein; COG: COG3140; Pfam: PF03701; InterPro: IPR005371; Belongs to the UPF0181 family. | Peptidase M16 inactive domain protein; COG: COG0612; Pfam: PF00675,PF05193; InterPro: IPR011237. | 0.759 |
| EFE94900.1 | thiK | HMPREF0758_3334 | HMPREF0758_4173 | Hypothetical protein; COG: COG3140; Pfam: PF03701; InterPro: IPR005371; Belongs to the UPF0181 family. | Putative thiamine diphosphokinase; Catalyzes the phosphorylation of thiamine to thiamine phosphate. | 0.744 |
| EFE94900.1 | wecF | HMPREF0758_3334 | HMPREF0758_1519 | Hypothetical protein; COG: COG3140; Pfam: PF03701; InterPro: IPR005371; Belongs to the UPF0181 family. | TDP-Fuc4NAc:lipid II Fuc4Nac transferase; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis; Belongs to the glycosyltransferase 56 family. | 0.772 |
| EFE96731.1 | EFE94900.1 | HMPREF0758_1590 | HMPREF0758_3334 | Hypothetical protein; COG: COG3776; Pfam: PF06611; InterPro: IPR009525. | Hypothetical protein; COG: COG3140; Pfam: PF03701; InterPro: IPR005371; Belongs to the UPF0181 family. | 0.773 |
| EFE96731.1 | LpoB | HMPREF0758_1590 | HMPREF0758_4174 | Hypothetical protein; COG: COG3776; Pfam: PF06611; InterPro: IPR009525. | Hypothetical protein; COG: COG3417. | 0.741 |
| EFE96731.1 | pqqL | HMPREF0758_1590 | HMPREF0758_1502 | Hypothetical protein; COG: COG3776; Pfam: PF06611; InterPro: IPR009525. | Peptidase M16 inactive domain protein; COG: COG0612; Pfam: PF00675,PF05193; InterPro: IPR011237. | 0.757 |
| EFE96731.1 | thiK | HMPREF0758_1590 | HMPREF0758_4173 | Hypothetical protein; COG: COG3776; Pfam: PF06611; InterPro: IPR009525. | Putative thiamine diphosphokinase; Catalyzes the phosphorylation of thiamine to thiamine phosphate. | 0.743 |
| EFE96731.1 | wecF | HMPREF0758_1590 | HMPREF0758_1519 | Hypothetical protein; COG: COG3776; Pfam: PF06611; InterPro: IPR009525. | TDP-Fuc4NAc:lipid II Fuc4Nac transferase; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis; Belongs to the glycosyltransferase 56 family. | 0.739 |
| EFE97975.1 | rsgA | HMPREF0758_0303 | HMPREF0758_0874 | TENA/THI-4 family protein; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4- amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2- methylpyrimidine (HMP); Belongs to the TenA family. | Ribosome small subunit-dependent GTPase A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. | 0.900 |
| EFE97975.1 | thiE | HMPREF0758_0303 | HMPREF0758_1669 | TENA/THI-4 family protein; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4- amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2- methylpyrimidine (HMP); Belongs to the TenA family. | Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.584 |
| EFE97975.1 | thiK | HMPREF0758_0303 | HMPREF0758_4173 | TENA/THI-4 family protein; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4- amino-5-aminomethyl-2-methylpyrimidine to 4-amino-5-hydroxymethyl-2- methylpyrimidine (HMP); Belongs to the TenA family. | Putative thiamine diphosphokinase; Catalyzes the phosphorylation of thiamine to thiamine phosphate. | 0.913 |
| LpoB | EFE94900.1 | HMPREF0758_4174 | HMPREF0758_3334 | Hypothetical protein; COG: COG3417. | Hypothetical protein; COG: COG3140; Pfam: PF03701; InterPro: IPR005371; Belongs to the UPF0181 family. | 0.491 |
| LpoB | EFE96731.1 | HMPREF0758_4174 | HMPREF0758_1590 | Hypothetical protein; COG: COG3417. | Hypothetical protein; COG: COG3776; Pfam: PF06611; InterPro: IPR009525. | 0.741 |
| LpoB | nagZ | HMPREF0758_4174 | HMPREF0758_4172 | Hypothetical protein; COG: COG3417. | Glycosyl hydrolase family 3 N-terminal domain protein; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.704 |
| LpoB | pqqL | HMPREF0758_4174 | HMPREF0758_1502 | Hypothetical protein; COG: COG3417. | Peptidase M16 inactive domain protein; COG: COG0612; Pfam: PF00675,PF05193; InterPro: IPR011237. | 0.563 |
| LpoB | thiK | HMPREF0758_4174 | HMPREF0758_4173 | Hypothetical protein; COG: COG3417. | Putative thiamine diphosphokinase; Catalyzes the phosphorylation of thiamine to thiamine phosphate. | 0.898 |
| LpoB | wecF | HMPREF0758_4174 | HMPREF0758_1519 | Hypothetical protein; COG: COG3417. | TDP-Fuc4NAc:lipid II Fuc4Nac transferase; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis; Belongs to the glycosyltransferase 56 family. | 0.721 |
| nagZ | LpoB | HMPREF0758_4172 | HMPREF0758_4174 | Glycosyl hydrolase family 3 N-terminal domain protein; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | Hypothetical protein; COG: COG3417. | 0.704 |