| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| amiB | dniR | HMPREF0758_0868 | HMPREF0758_0374 | N-acetylmuramoyl-L-alanine amidase; COG: COG0860; Pfam: PF01520,PF01476; InterPro: IPR002508. | Transglycosylase SLT domain protein; COG: COG0741; Pfam: PF06474,PF01464,PF01476; InterPro: IPR008258. | 0.636 |
| amiB | ftsA | HMPREF0758_0868 | HMPREF0758_0509 | N-acetylmuramoyl-L-alanine amidase; COG: COG0860; Pfam: PF01520,PF01476; InterPro: IPR002508. | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | 0.641 |
| amiB | mltG | HMPREF0758_0868 | HMPREF0758_4183 | N-acetylmuramoyl-L-alanine amidase; COG: COG0860; Pfam: PF01520,PF01476; InterPro: IPR002508. | YceG family protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | 0.621 |
| amiB | mrcB | HMPREF0758_0868 | HMPREF0758_2168 | N-acetylmuramoyl-L-alanine amidase; COG: COG0860; Pfam: PF01520,PF01476; InterPro: IPR002508. | Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.566 |
| amiB | mtgA | HMPREF0758_0868 | HMPREF0758_1882 | N-acetylmuramoyl-L-alanine amidase; COG: COG0860; Pfam: PF01520,PF01476; InterPro: IPR002508. | Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. | 0.587 |
| dniR | amiB | HMPREF0758_0374 | HMPREF0758_0868 | Transglycosylase SLT domain protein; COG: COG0741; Pfam: PF06474,PF01464,PF01476; InterPro: IPR008258. | N-acetylmuramoyl-L-alanine amidase; COG: COG0860; Pfam: PF01520,PF01476; InterPro: IPR002508. | 0.636 |
| dniR | ftsA | HMPREF0758_0374 | HMPREF0758_0509 | Transglycosylase SLT domain protein; COG: COG0741; Pfam: PF06474,PF01464,PF01476; InterPro: IPR008258. | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | 0.511 |
| dniR | mltG | HMPREF0758_0374 | HMPREF0758_4183 | Transglycosylase SLT domain protein; COG: COG0741; Pfam: PF06474,PF01464,PF01476; InterPro: IPR008258. | YceG family protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | 0.604 |
| dniR | mrcB | HMPREF0758_0374 | HMPREF0758_2168 | Transglycosylase SLT domain protein; COG: COG0741; Pfam: PF06474,PF01464,PF01476; InterPro: IPR008258. | Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.526 |
| dniR | mtgA | HMPREF0758_0374 | HMPREF0758_1882 | Transglycosylase SLT domain protein; COG: COG0741; Pfam: PF06474,PF01464,PF01476; InterPro: IPR008258. | Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. | 0.435 |
| ftsA | amiB | HMPREF0758_0509 | HMPREF0758_0868 | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | N-acetylmuramoyl-L-alanine amidase; COG: COG0860; Pfam: PF01520,PF01476; InterPro: IPR002508. | 0.641 |
| ftsA | dniR | HMPREF0758_0509 | HMPREF0758_0374 | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | Transglycosylase SLT domain protein; COG: COG0741; Pfam: PF06474,PF01464,PF01476; InterPro: IPR008258. | 0.511 |
| ftsA | mltG | HMPREF0758_0509 | HMPREF0758_4183 | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | YceG family protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | 0.564 |
| ftsA | mrcB | HMPREF0758_0509 | HMPREF0758_2168 | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.443 |
| holB | mltG | HMPREF0758_4181 | HMPREF0758_4183 | DNA polymerase III, delta' subunit; COG: COG0470; Pfam: PF09115; InterPro: IPR004622. | YceG family protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | 0.843 |
| holB | pabC | HMPREF0758_4181 | HMPREF0758_4184 | DNA polymerase III, delta' subunit; COG: COG0470; Pfam: PF09115; InterPro: IPR004622. | Aminodeoxychorismate lyase; COG: COG0115; Pfam: PF01063; InterPro: IPR001544. | 0.792 |
| holB | tmk | HMPREF0758_4181 | HMPREF0758_4182 | DNA polymerase III, delta' subunit; COG: COG0470; Pfam: PF09115; InterPro: IPR004622. | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.952 |
| holB | ycfH | HMPREF0758_4181 | HMPREF0758_4180 | DNA polymerase III, delta' subunit; COG: COG0470; Pfam: PF09115; InterPro: IPR004622. | Hydrolase, TatD family; COG: COG0084; Pfam: PF01026; InterPro: IPR001130. | 0.844 |
| mltG | amiB | HMPREF0758_4183 | HMPREF0758_0868 | YceG family protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | N-acetylmuramoyl-L-alanine amidase; COG: COG0860; Pfam: PF01520,PF01476; InterPro: IPR002508. | 0.621 |
| mltG | dniR | HMPREF0758_4183 | HMPREF0758_0374 | YceG family protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | Transglycosylase SLT domain protein; COG: COG0741; Pfam: PF06474,PF01464,PF01476; InterPro: IPR008258. | 0.604 |