| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| NadR_1 | cinA3 | HMPREF0758_0608 | HMPREF0758_4233 | Nicotinamide-nucleotide adenylyltransferase; COG: COG3172; Pfam: PF01381; InterPro: IPR006417. | Competence/damage-inducible domain protein CinA; COG: COG1546; Pfam: PF02464; InterPro: IPR008136; Belongs to the CinA family. | 0.505 |
| NadR_1 | nadD | HMPREF0758_0608 | HMPREF0758_4913 | Nicotinamide-nucleotide adenylyltransferase; COG: COG3172; Pfam: PF01381; InterPro: IPR006417. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.941 |
| NadR_1 | nadE | HMPREF0758_0608 | HMPREF0758_2475 | Nicotinamide-nucleotide adenylyltransferase; COG: COG3172; Pfam: PF01381; InterPro: IPR006417. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.956 |
| amiC2 | cinA3 | HMPREF0758_2643 | HMPREF0758_4233 | N-acetylmuramoyl-L-alanine amidase; COG: COG0860; Pfam: PF01520; InterPro: IPR002508. | Competence/damage-inducible domain protein CinA; COG: COG1546; Pfam: PF02464; InterPro: IPR008136; Belongs to the CinA family. | 0.409 |
| cinA2 | cinA3 | HMPREF0758_2826 | HMPREF0758_4233 | Competence/damage-inducible domain protein CinA; COG: COG1058; Pfam: PF00994; InterPro: IPR008135; Belongs to the CinA family. | Competence/damage-inducible domain protein CinA; COG: COG1546; Pfam: PF02464; InterPro: IPR008136; Belongs to the CinA family. | 0.447 |
| cinA2 | nadD | HMPREF0758_2826 | HMPREF0758_4913 | Competence/damage-inducible domain protein CinA; COG: COG1058; Pfam: PF00994; InterPro: IPR008135; Belongs to the CinA family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.497 |
| cinA2 | nadE | HMPREF0758_2826 | HMPREF0758_2475 | Competence/damage-inducible domain protein CinA; COG: COG1058; Pfam: PF00994; InterPro: IPR008135; Belongs to the CinA family. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.493 |
| cinA2 | pgsA | HMPREF0758_2826 | HMPREF0758_4263 | Competence/damage-inducible domain protein CinA; COG: COG1058; Pfam: PF00994; InterPro: IPR008135; Belongs to the CinA family. | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.625 |
| cinA2 | rec | HMPREF0758_2826 | HMPREF0758_4381 | Competence/damage-inducible domain protein CinA; COG: COG1058; Pfam: PF00994; InterPro: IPR008135; Belongs to the CinA family. | DNA internalization competence protein ComEC/Rec2-like protein; Pfam: PF03772,PF00753; InterPro: IPR004797. | 0.429 |
| cinA3 | NadR_1 | HMPREF0758_4233 | HMPREF0758_0608 | Competence/damage-inducible domain protein CinA; COG: COG1546; Pfam: PF02464; InterPro: IPR008136; Belongs to the CinA family. | Nicotinamide-nucleotide adenylyltransferase; COG: COG3172; Pfam: PF01381; InterPro: IPR006417. | 0.505 |
| cinA3 | amiC2 | HMPREF0758_4233 | HMPREF0758_2643 | Competence/damage-inducible domain protein CinA; COG: COG1546; Pfam: PF02464; InterPro: IPR008136; Belongs to the CinA family. | N-acetylmuramoyl-L-alanine amidase; COG: COG0860; Pfam: PF01520; InterPro: IPR002508. | 0.409 |
| cinA3 | cinA2 | HMPREF0758_4233 | HMPREF0758_2826 | Competence/damage-inducible domain protein CinA; COG: COG1546; Pfam: PF02464; InterPro: IPR008136; Belongs to the CinA family. | Competence/damage-inducible domain protein CinA; COG: COG1058; Pfam: PF00994; InterPro: IPR008135; Belongs to the CinA family. | 0.447 |
| cinA3 | nadD | HMPREF0758_4233 | HMPREF0758_4913 | Competence/damage-inducible domain protein CinA; COG: COG1546; Pfam: PF02464; InterPro: IPR008136; Belongs to the CinA family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.510 |
| cinA3 | nadE | HMPREF0758_4233 | HMPREF0758_2475 | Competence/damage-inducible domain protein CinA; COG: COG1546; Pfam: PF02464; InterPro: IPR008136; Belongs to the CinA family. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.495 |
| cinA3 | pgsA | HMPREF0758_4233 | HMPREF0758_4263 | Competence/damage-inducible domain protein CinA; COG: COG1546; Pfam: PF02464; InterPro: IPR008136; Belongs to the CinA family. | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.437 |
| cinA3 | rec | HMPREF0758_4233 | HMPREF0758_4381 | Competence/damage-inducible domain protein CinA; COG: COG1546; Pfam: PF02464; InterPro: IPR008136; Belongs to the CinA family. | DNA internalization competence protein ComEC/Rec2-like protein; Pfam: PF03772,PF00753; InterPro: IPR004797. | 0.443 |
| nadD | NadR_1 | HMPREF0758_4913 | HMPREF0758_0608 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Nicotinamide-nucleotide adenylyltransferase; COG: COG3172; Pfam: PF01381; InterPro: IPR006417. | 0.941 |
| nadD | cinA2 | HMPREF0758_4913 | HMPREF0758_2826 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Competence/damage-inducible domain protein CinA; COG: COG1058; Pfam: PF00994; InterPro: IPR008135; Belongs to the CinA family. | 0.497 |
| nadD | cinA3 | HMPREF0758_4913 | HMPREF0758_4233 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Competence/damage-inducible domain protein CinA; COG: COG1546; Pfam: PF02464; InterPro: IPR008136; Belongs to the CinA family. | 0.510 |
| nadD | nadE | HMPREF0758_4913 | HMPREF0758_2475 | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.952 |