| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFE94207.1 | phoH | HMPREF0758_4302 | HMPREF0758_4303 | Beta-hydroxylase, aspartyl/asparaginyl family; COG: COG3555; Pfam: PF05118; InterPro: IPR007803. | PhoH family protein; COG: COG1702; Pfam: PF02562; InterPro: IPR003714. | 0.741 |
| clpX | phoH | HMPREF0758_0200 | HMPREF0758_4303 | ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | PhoH family protein; COG: COG1702; Pfam: PF02562; InterPro: IPR003714. | 0.509 |
| era | phoH | HMPREF0758_2456 | HMPREF0758_4303 | Ribosome biogenesis GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | PhoH family protein; COG: COG1702; Pfam: PF02562; InterPro: IPR003714. | 0.409 |
| era | recO | HMPREF0758_2456 | HMPREF0758_2457 | Ribosome biogenesis GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.930 |
| era | sun | HMPREF0758_2456 | HMPREF0758_0930 | Ribosome biogenesis GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.602 |
| era | ybeY | HMPREF0758_2456 | HMPREF0758_4900 | Ribosome biogenesis GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Translation metalloprotein YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.839 |
| lnt | phoH | HMPREF0758_4902 | HMPREF0758_4303 | Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. | PhoH family protein; COG: COG1702; Pfam: PF02562; InterPro: IPR003714. | 0.431 |
| lnt | ybeY | HMPREF0758_4902 | HMPREF0758_4900 | Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. | Translation metalloprotein YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.700 |
| phoH | EFE94207.1 | HMPREF0758_4303 | HMPREF0758_4302 | PhoH family protein; COG: COG1702; Pfam: PF02562; InterPro: IPR003714. | Beta-hydroxylase, aspartyl/asparaginyl family; COG: COG3555; Pfam: PF05118; InterPro: IPR007803. | 0.741 |
| phoH | clpX | HMPREF0758_4303 | HMPREF0758_0200 | PhoH family protein; COG: COG1702; Pfam: PF02562; InterPro: IPR003714. | ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.509 |
| phoH | era | HMPREF0758_4303 | HMPREF0758_2456 | PhoH family protein; COG: COG1702; Pfam: PF02562; InterPro: IPR003714. | Ribosome biogenesis GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.409 |
| phoH | lnt | HMPREF0758_4303 | HMPREF0758_4902 | PhoH family protein; COG: COG1702; Pfam: PF02562; InterPro: IPR003714. | Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. | 0.431 |
| phoH | recO | HMPREF0758_4303 | HMPREF0758_2457 | PhoH family protein; COG: COG1702; Pfam: PF02562; InterPro: IPR003714. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.664 |
| phoH | sun | HMPREF0758_4303 | HMPREF0758_0930 | PhoH family protein; COG: COG1702; Pfam: PF02562; InterPro: IPR003714. | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.427 |
| phoH | tadA | HMPREF0758_4303 | HMPREF0758_2467 | PhoH family protein; COG: COG1702; Pfam: PF02562; InterPro: IPR003714. | Cytidine and deoxycytidylate deaminase zinc-binding region; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.582 |
| phoH | ybeY | HMPREF0758_4303 | HMPREF0758_4900 | PhoH family protein; COG: COG1702; Pfam: PF02562; InterPro: IPR003714. | Translation metalloprotein YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.833 |
| recO | era | HMPREF0758_2457 | HMPREF0758_2456 | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | Ribosome biogenesis GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.930 |
| recO | phoH | HMPREF0758_2457 | HMPREF0758_4303 | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | PhoH family protein; COG: COG1702; Pfam: PF02562; InterPro: IPR003714. | 0.664 |
| recO | sun | HMPREF0758_2457 | HMPREF0758_0930 | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.443 |
| recO | ybeY | HMPREF0758_2457 | HMPREF0758_4900 | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | Translation metalloprotein YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.441 |