STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
fabABeta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. (172 aa)    
Predicted Functional Partners:
fabI
Enoyl-[acyl-carrier-protein] reductase (NADH); COG: COG0623; Pfam: PF00106; InterPro: IPR014358.
  
 
 0.955
fabV
Short-chain alcohol dehydrogenase; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family.
  
 
 0.949
fabZ
Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
  
 
 0.946
fabB-2
Beta-ketoacyl synthase, N-terminal domain protein; COG: COG0304; Pfam: PF00109,PF02801; InterPro: IPR000794; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 
 0.934
fabG
Putative 3-oxoacyl-(acyl-carrier-protein) reductase; COG: COG1028; Pfam: PF00106; InterPro: IPR016040.
  
 0.921
fabG3
Putative 3-oxoacyl-[acyl-carrier-protein] reductase; COG: COG1028; Pfam: PF00106; InterPro: IPR016040.
  
 0.921
fabG-2
3-oxoacyl-[acyl-carrier-protein] reductase; COG: COG1028; Pfam: PF00106; InterPro: IPR016040.
  
 0.921
fabG11
Oxidoreductase, short chain dehydrogenase/reductase family protein; COG: COG1028; Pfam: PF00106; InterPro: IPR016040.
  
 0.921
fabG-3
3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 0.921
fabG19
Oxidoreductase, short chain dehydrogenase/reductase family protein; COG: COG1028; Pfam: PF00106; InterPro: IPR016040.
  
 0.921
Your Current Organism:
Serratia odorifera
NCBI taxonomy Id: 667129
Other names: S. odorifera DSM 4582, Serratia odorifera DSM 4582, Serratia odorifera str. DSM 4582, Serratia odorifera strain DSM 4582
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