| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFE94250.1 | EFE94251.1 | HMPREF0758_4345 | HMPREF0758_4346 | Hypothetical protein; COG: COG3009; Pfam: PF03886; InterPro: IPR005586. | Hypothetical protein; COG: COG3008; Pfam: PF02470; InterPro: IPR003399. | 0.954 |
| EFE94250.1 | EFE94253.1 | HMPREF0758_4345 | HMPREF0758_4348 | Hypothetical protein; COG: COG3009; Pfam: PF03886; InterPro: IPR005586. | ABC transporter, ATP-binding protein; COG: COG0488; Pfam: PF00005; InterPro: IPR003593. | 0.564 |
| EFE94250.1 | pqiA2 | HMPREF0758_4345 | HMPREF0758_4347 | Hypothetical protein; COG: COG3009; Pfam: PF03886; InterPro: IPR005586. | Integral membrane protein, PqiA family; COG: COG2995; Pfam: PF04403; InterPro: IPR005219. | 0.954 |
| EFE94250.1 | rlmL | HMPREF0758_4345 | HMPREF0758_4349 | Hypothetical protein; COG: COG3009; Pfam: PF03886; InterPro: IPR005586. | THUMP domain protein; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.623 |
| EFE94251.1 | EFE94250.1 | HMPREF0758_4346 | HMPREF0758_4345 | Hypothetical protein; COG: COG3008; Pfam: PF02470; InterPro: IPR003399. | Hypothetical protein; COG: COG3009; Pfam: PF03886; InterPro: IPR005586. | 0.954 |
| EFE94251.1 | EFE94253.1 | HMPREF0758_4346 | HMPREF0758_4348 | Hypothetical protein; COG: COG3008; Pfam: PF02470; InterPro: IPR003399. | ABC transporter, ATP-binding protein; COG: COG0488; Pfam: PF00005; InterPro: IPR003593. | 0.564 |
| EFE94251.1 | pqiA2 | HMPREF0758_4346 | HMPREF0758_4347 | Hypothetical protein; COG: COG3008; Pfam: PF02470; InterPro: IPR003399. | Integral membrane protein, PqiA family; COG: COG2995; Pfam: PF04403; InterPro: IPR005219. | 0.960 |
| EFE94251.1 | rlmL | HMPREF0758_4346 | HMPREF0758_4349 | Hypothetical protein; COG: COG3008; Pfam: PF02470; InterPro: IPR003399. | THUMP domain protein; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.620 |
| EFE94253.1 | EFE94250.1 | HMPREF0758_4348 | HMPREF0758_4345 | ABC transporter, ATP-binding protein; COG: COG0488; Pfam: PF00005; InterPro: IPR003593. | Hypothetical protein; COG: COG3009; Pfam: PF03886; InterPro: IPR005586. | 0.564 |
| EFE94253.1 | EFE94251.1 | HMPREF0758_4348 | HMPREF0758_4346 | ABC transporter, ATP-binding protein; COG: COG0488; Pfam: PF00005; InterPro: IPR003593. | Hypothetical protein; COG: COG3008; Pfam: PF02470; InterPro: IPR003399. | 0.564 |
| EFE94253.1 | pqiA2 | HMPREF0758_4348 | HMPREF0758_4347 | ABC transporter, ATP-binding protein; COG: COG0488; Pfam: PF00005; InterPro: IPR003593. | Integral membrane protein, PqiA family; COG: COG2995; Pfam: PF04403; InterPro: IPR005219. | 0.564 |
| EFE94253.1 | rlmL | HMPREF0758_4348 | HMPREF0758_4349 | ABC transporter, ATP-binding protein; COG: COG0488; Pfam: PF00005; InterPro: IPR003593. | THUMP domain protein; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.883 |
| pnp | rlmL | HMPREF0758_0801 | HMPREF0758_4349 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | THUMP domain protein; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.571 |
| pnp | sun | HMPREF0758_0801 | HMPREF0758_0930 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.477 |
| pnp | uppS | HMPREF0758_0801 | HMPREF0758_2336 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | Di-trans,poly-cis-decaprenylcistransferase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.696 |
| pqiA2 | EFE94250.1 | HMPREF0758_4347 | HMPREF0758_4345 | Integral membrane protein, PqiA family; COG: COG2995; Pfam: PF04403; InterPro: IPR005219. | Hypothetical protein; COG: COG3009; Pfam: PF03886; InterPro: IPR005586. | 0.954 |
| pqiA2 | EFE94251.1 | HMPREF0758_4347 | HMPREF0758_4346 | Integral membrane protein, PqiA family; COG: COG2995; Pfam: PF04403; InterPro: IPR005219. | Hypothetical protein; COG: COG3008; Pfam: PF02470; InterPro: IPR003399. | 0.960 |
| pqiA2 | EFE94253.1 | HMPREF0758_4347 | HMPREF0758_4348 | Integral membrane protein, PqiA family; COG: COG2995; Pfam: PF04403; InterPro: IPR005219. | ABC transporter, ATP-binding protein; COG: COG0488; Pfam: PF00005; InterPro: IPR003593. | 0.564 |
| pqiA2 | rlmL | HMPREF0758_4347 | HMPREF0758_4349 | Integral membrane protein, PqiA family; COG: COG2995; Pfam: PF04403; InterPro: IPR005219. | THUMP domain protein; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.622 |
| ribD | rlmL | HMPREF0758_0227 | HMPREF0758_4349 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | THUMP domain protein; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. | 0.601 |