STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
macBABC transporter, ATP-binding protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. (648 aa)    
Predicted Functional Partners:
macA
Efflux transporter, RND family, MFP subunit; COG: COG0845; Pfam: PF00529; InterPro: IPR006143; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.998
bpeA
Efflux transporter, RND family, MFP subunit; COG: COG0845; Pfam: PF00529; InterPro: IPR006143; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.980
mdtA
Efflux transporter, RND family, MFP subunit; COG: COG0845; Pfam: PF00529; InterPro: IPR006143; overlaps another CDS with the same product name; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.978
MexA
Efflux transporter, RND family, MFP subunit; COG: COG0845; Pfam: PF00529; InterPro: IPR006143; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 
 0.975
lolE
Lipoprotein releasing system, transmembrane protein LolE; COG: COG4591; Pfam: PF02687; InterPro: IPR011925.
  
 
 0.937
lolC
Lipoprotein releasing system, transmembrane protein, LolC/E family; COG: COG4591; Pfam: PF02687; InterPro: IPR011925.
  
 
 0.937
OprM
Efflux transporter, outer membrane factor lipoprotein, NodT family; COG: COG1538; Pfam: PF02321; InterPro: IPR010131.
 
 
 0.907
MdtP
Efflux transporter, outer membrane factor lipoprotein, NodT family; COG: COG1538; Pfam: PF02321; InterPro: IPR010131.
  
 
 0.894
tolC
Type I secretion outer membrane protein, TolC family; COG: COG1538; Pfam: PF02321; InterPro: IPR010130.
  
 
 0.892
tliF
Type I secretion outer membrane protein, TolC family; COG: COG1538; Pfam: PF02321; InterPro: IPR010130.
  
 
 0.892
Your Current Organism:
Serratia odorifera
NCBI taxonomy Id: 667129
Other names: S. odorifera DSM 4582, Serratia odorifera DSM 4582, Serratia odorifera str. DSM 4582, Serratia odorifera strain DSM 4582
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