STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hcr2Fe-2S iron-sulfur cluster binding domain protein; COG: COG1018; Pfam: PF00970,PF00175,PF00111; InterPro: IPR001041. (323 aa)    
Predicted Functional Partners:
nuoD
NADH dehydrogenase subunit D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family.
  
 
 0.940
hcp
Hydroxylamine reductase; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
  
  
 0.891
YcbX_2
MOSC domain protein; COG: COG3217; Pfam: PF03476,PF03473,PF00111; InterPro: IPR005302.
  
 0.885
fadH
Pyridine nucleotide-disulfide oxidoreductase; COG: COG1902; Pfam: PF00724,PF07992,PF00070; InterPro: IPR013785.
  
 0.733
iscU
FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
  
 0.701
nirB-2
Nitrite reductase [NAD(P)H], large subunit; COG: COG1251; Pfam: PF07992,PF00070,PF04324,PF03460,PF01077; InterPro: IPR012744; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
  
 0.694
paaN
Phenylacetic acid degradation protein paaN; Pfam: PF00171,PF01575; InterPro: IPR011966.
 
  
 0.690
nifJ
Pyruvate synthase; COG: COG0674; Pfam: PF01855,PF01558,PF00037,PF02775; InterPro: IPR011895.
  
 
 0.688
yhgI
IscR-regulated protein YhgI; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
 
 0.681
paaH
phenylacetate-CoA oxygenase, PaaH subunit; COG: COG3460; Pfam: PF06243; InterPro: IPR009359.
 
  
 0.680
Your Current Organism:
Serratia odorifera
NCBI taxonomy Id: 667129
Other names: S. odorifera DSM 4582, Serratia odorifera DSM 4582, Serratia odorifera str. DSM 4582, Serratia odorifera strain DSM 4582
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