STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prtCType I secretion membrane fusion protein, HlyD family; COG: COG0845; Pfam: PF00529; InterPro: IPR010129. (443 aa)    
Predicted Functional Partners:
tliD
Type I secretion system ATPase; COG: COG4618; Pfam: PF00005; InterPro: IPR010128.
  
 0.948
tliF
Type I secretion outer membrane protein, TolC family; COG: COG1538; Pfam: PF02321; InterPro: IPR010130.
 
 
 0.936
macB
ABC transporter, ATP-binding protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.839
aprA
Serralysin; COG: COG2931; Pfam: PF00413,PF08548,PF00353; InterPro: IPR013858.
 
  
 0.793
tolC
Type I secretion outer membrane protein, TolC family; COG: COG1538; Pfam: PF02321; InterPro: IPR010130.
  
 
 0.589
MdtP
Efflux transporter, outer membrane factor lipoprotein, NodT family; COG: COG1538; Pfam: PF02321; InterPro: IPR010131.
  
 
 0.589
OprM
Efflux transporter, outer membrane factor lipoprotein, NodT family; COG: COG1538; Pfam: PF02321; InterPro: IPR010131.
  
 
 0.589
cyoB
Cytochrome o ubiquinol oxidase, subunit I; COG: COG0843; Pfam: PF00115; InterPro: IPR014207; Belongs to the heme-copper respiratory oxidase family.
 
      0.453
pueA
Type I secretion target GGXGXDXXX repeat (2 copies); Pfam: PF00353.
 
  
 0.425
mobA
Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family.
  
    0.403
Your Current Organism:
Serratia odorifera
NCBI taxonomy Id: 667129
Other names: S. odorifera DSM 4582, Serratia odorifera DSM 4582, Serratia odorifera str. DSM 4582, Serratia odorifera strain DSM 4582
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