| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFE93711.1 | adhC | HMPREF0758_4595 | HMPREF0758_4597 | Hypothetical protein; Pfam: PF06779; InterPro: IPR010645. | S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; COG: COG1062; Pfam: PF08240,PF00107; InterPro: IPR014183; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | 0.521 |
| EFE93711.1 | fghA | HMPREF0758_4595 | HMPREF0758_4598 | Hypothetical protein; Pfam: PF06779; InterPro: IPR010645. | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. | 0.486 |
| EFE93711.1 | lysR9 | HMPREF0758_4595 | HMPREF0758_4596 | Hypothetical protein; Pfam: PF06779; InterPro: IPR010645. | LysR substrate binding domain protein; COG: COG0583; Pfam: PF00126,PF03466; InterPro: IPR005119; Belongs to the LysR transcriptional regulatory family. | 0.543 |
| FrmR | XylB_3 | HMPREF0758_4801 | HMPREF0758_4699 | Hypothetical protein; COG: COG1937; Pfam: PF02583; InterPro: IPR003735. | Oxidoreductase, zinc-binding dehydrogenase family protein; COG: COG1062; Pfam: PF00107; InterPro: IPR002085. | 0.669 |
| FrmR | adhC | HMPREF0758_4801 | HMPREF0758_4597 | Hypothetical protein; COG: COG1937; Pfam: PF02583; InterPro: IPR003735. | S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; COG: COG1062; Pfam: PF08240,PF00107; InterPro: IPR014183; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | 0.669 |
| FrmR | fghA | HMPREF0758_4801 | HMPREF0758_4598 | Hypothetical protein; COG: COG1937; Pfam: PF02583; InterPro: IPR003735. | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. | 0.657 |
| XylB_3 | FrmR | HMPREF0758_4699 | HMPREF0758_4801 | Oxidoreductase, zinc-binding dehydrogenase family protein; COG: COG1062; Pfam: PF00107; InterPro: IPR002085. | Hypothetical protein; COG: COG1937; Pfam: PF02583; InterPro: IPR003735. | 0.669 |
| XylB_3 | fghA | HMPREF0758_4699 | HMPREF0758_4598 | Oxidoreductase, zinc-binding dehydrogenase family protein; COG: COG1062; Pfam: PF00107; InterPro: IPR002085. | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. | 0.918 |
| adhC | EFE93711.1 | HMPREF0758_4597 | HMPREF0758_4595 | S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; COG: COG1062; Pfam: PF08240,PF00107; InterPro: IPR014183; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | Hypothetical protein; Pfam: PF06779; InterPro: IPR010645. | 0.521 |
| adhC | FrmR | HMPREF0758_4597 | HMPREF0758_4801 | S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; COG: COG1062; Pfam: PF08240,PF00107; InterPro: IPR014183; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | Hypothetical protein; COG: COG1937; Pfam: PF02583; InterPro: IPR003735. | 0.669 |
| adhC | fghA | HMPREF0758_4597 | HMPREF0758_4598 | S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; COG: COG1062; Pfam: PF08240,PF00107; InterPro: IPR014183; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. | 0.999 |
| adhC | gst6 | HMPREF0758_4597 | HMPREF0758_4617 | S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; COG: COG1062; Pfam: PF08240,PF00107; InterPro: IPR014183; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | Glutathione S-transferase, C-terminal domain protein; COG: COG0625; Pfam: PF02798,PF00043; InterPro: IPR010987; Belongs to the GST superfamily. | 0.557 |
| adhC | lysR9 | HMPREF0758_4597 | HMPREF0758_4596 | S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; COG: COG1062; Pfam: PF08240,PF00107; InterPro: IPR014183; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. | LysR substrate binding domain protein; COG: COG0583; Pfam: PF00126,PF03466; InterPro: IPR005119; Belongs to the LysR transcriptional regulatory family. | 0.689 |
| fdh | fghA | HMPREF0758_0678 | HMPREF0758_4598 | GroES-like protein; COG: COG1063; Pfam: PF08240,PF00107; InterPro: IPR002085. | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. | 0.575 |
| fdnI | fdxH | HMPREF0758_1417 | HMPREF0758_1416 | Formate dehydrogenase, gamma subunit; COG: COG2864; Pfam: PF01292; InterPro: IPR006471. | Formate dehydrogenase, beta subunit; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. | 0.999 |
| fdnI | fghA | HMPREF0758_1417 | HMPREF0758_4598 | Formate dehydrogenase, gamma subunit; COG: COG2864; Pfam: PF01292; InterPro: IPR006471. | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. | 0.900 |
| fdxH | fdnI | HMPREF0758_1416 | HMPREF0758_1417 | Formate dehydrogenase, beta subunit; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. | Formate dehydrogenase, gamma subunit; COG: COG2864; Pfam: PF01292; InterPro: IPR006471. | 0.999 |
| fdxH | fghA | HMPREF0758_1416 | HMPREF0758_4598 | Formate dehydrogenase, beta subunit; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. | 0.900 |
| fghA | EFE93711.1 | HMPREF0758_4598 | HMPREF0758_4595 | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. | Hypothetical protein; Pfam: PF06779; InterPro: IPR010645. | 0.486 |
| fghA | FrmR | HMPREF0758_4598 | HMPREF0758_4801 | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. | Hypothetical protein; COG: COG1937; Pfam: PF02583; InterPro: IPR003735. | 0.657 |