STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ucaUrea carboxylase; COG: COG0439; Pfam: PF00289,PF02786,PF02785,PF02626,PF02682,PF00364; InterPro: IPR014084. (1245 aa)    
Predicted Functional Partners:
atzF
Allophanate hydrolase; COG: COG0154; Pfam: PF01425; InterPro: IPR014085.
  
 0.998
ybgL
LamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
 
  
 0.991
accB
acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
 
 0.978
dur
Biotin-dependent carboxylase domain protein; COG: COG1984; Pfam: PF02626; InterPro: IPR003778.
 
 
0.948
KdgR_1
IclR helix-turn-helix domain protein; Pfam: PF09339,PF01614; InterPro: IPR014757.
  
    0.942
iclR
Transcriptional regulator, IclR family, C-terminal domain protein; COG: COG1414; Pfam: PF09339,PF01614; InterPro: IPR014757.
  
    0.942
KdgR_2
IclR helix-turn-helix domain protein; COG: COG1414; Pfam: PF09339,PF01614; InterPro: IPR005471.
  
    0.942
kdgR
Pectin degradation repressor protein KdgR; COG: COG1414; Pfam: PF09339,PF01614; InterPro: IPR014757.
  
    0.942
ybgJ
TIGR00370 family protein; COG: COG2049; Pfam: PF02682; InterPro: IPR010016.
 
 
0.936
birA
biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
 
  
 0.923
Your Current Organism:
Serratia odorifera
NCBI taxonomy Id: 667129
Other names: S. odorifera DSM 4582, Serratia odorifera DSM 4582, Serratia odorifera str. DSM 4582, Serratia odorifera strain DSM 4582
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