STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ydeVCarbohydrate kinase, FGGY family protein; Catalyzes the phosphorylation of autoinducer-2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3-dione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position. (521 aa)    
Predicted Functional Partners:
lsrG
Antibiotic biosynthesis monooxygenase; Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the conversion of (4S)-4-hydroxy-5- phosphonooxypentane-2,3-dione (P-DPD) to 3-hydroxy-5- phosphonooxypentane-2,4-dione (P-HPD); Belongs to the LsrG family.
 
 
 0.925
rhaA
L-rhamnose isomerase; COG: COG4806; Pfam: PF06134; InterPro: IPR009308.
 
  
 0.653
ptsH
Phosphocarrier protein HPr; COG: COG1925; Pfam: PF00381; InterPro: IPR000032.
    
 
 0.612
EFE97733.1
Hypothetical protein.
  
  
 0.565
rhaU
L-rhamnose 1-epimerase; Involved in the anomeric conversion of L-rhamnose.
  
  
 0.565
LsrB
Hypothetical protein; COG: COG1879.
 
  
 0.499
ptsP
Phosphoenolpyruvate-protein phosphotransferase; COG: COG1080; Pfam: PF00381,PF05524,PF00391,PF02896,PF00359; InterPro: IPR006318.
   
 
 0.492
LsrF
Deoxyribose-phosphate aldolase; COG: COG1830; Pfam: PF01791; InterPro: IPR013785.
  
  
 0.442
NepI_4
Transporter, major facilitator family protein; COG: COG2814; Pfam: PF07690; InterPro: IPR011701.
  
    0.431
glpA
Glycerol-3-phosphate dehydrogenase, anaerobic, A subunit; COG: COG0578; Pfam: PF01266; InterPro: IPR006076; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
 
  
 0.430
Your Current Organism:
Serratia odorifera
NCBI taxonomy Id: 667129
Other names: S. odorifera DSM 4582, Serratia odorifera DSM 4582, Serratia odorifera str. DSM 4582, Serratia odorifera strain DSM 4582
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