| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BenM_4 | DmlR_39 | HMPREF0758_4745 | HMPREF0758_4746 | Transcriptional regulator, LysR family; COG: COG0583; Pfam: PF00126; InterPro: IPR011991; Belongs to the LysR transcriptional regulatory family. | Hypothetical protein; COG: COG0583; Pfam: PF03466; InterPro: IPR005119. | 0.938 |
| BenM_4 | NepI_4 | HMPREF0758_4745 | HMPREF0758_4744 | Transcriptional regulator, LysR family; COG: COG0583; Pfam: PF00126; InterPro: IPR011991; Belongs to the LysR transcriptional regulatory family. | Transporter, major facilitator family protein; COG: COG2814; Pfam: PF07690; InterPro: IPR011701. | 0.603 |
| BenM_4 | yajD | HMPREF0758_4745 | HMPREF0758_4747 | Transcriptional regulator, LysR family; COG: COG0583; Pfam: PF00126; InterPro: IPR011991; Belongs to the LysR transcriptional regulatory family. | HNH endonuclease domain protein; Pfam: PF01844. | 0.525 |
| DmlR_39 | BenM_4 | HMPREF0758_4746 | HMPREF0758_4745 | Hypothetical protein; COG: COG0583; Pfam: PF03466; InterPro: IPR005119. | Transcriptional regulator, LysR family; COG: COG0583; Pfam: PF00126; InterPro: IPR011991; Belongs to the LysR transcriptional regulatory family. | 0.938 |
| DmlR_39 | NepI_4 | HMPREF0758_4746 | HMPREF0758_4744 | Hypothetical protein; COG: COG0583; Pfam: PF03466; InterPro: IPR005119. | Transporter, major facilitator family protein; COG: COG2814; Pfam: PF07690; InterPro: IPR011701. | 0.556 |
| DmlR_39 | yajD | HMPREF0758_4746 | HMPREF0758_4747 | Hypothetical protein; COG: COG0583; Pfam: PF03466; InterPro: IPR005119. | HNH endonuclease domain protein; Pfam: PF01844. | 0.568 |
| NepI_4 | BenM_4 | HMPREF0758_4744 | HMPREF0758_4745 | Transporter, major facilitator family protein; COG: COG2814; Pfam: PF07690; InterPro: IPR011701. | Transcriptional regulator, LysR family; COG: COG0583; Pfam: PF00126; InterPro: IPR011991; Belongs to the LysR transcriptional regulatory family. | 0.603 |
| NepI_4 | DmlR_39 | HMPREF0758_4744 | HMPREF0758_4746 | Transporter, major facilitator family protein; COG: COG2814; Pfam: PF07690; InterPro: IPR011701. | Hypothetical protein; COG: COG0583; Pfam: PF03466; InterPro: IPR005119. | 0.556 |
| NepI_4 | cynX | HMPREF0758_4744 | HMPREF0758_1441 | Transporter, major facilitator family protein; COG: COG2814; Pfam: PF07690; InterPro: IPR011701. | Transporter, major facilitator family protein; COG: COG2807; Pfam: PF07690; InterPro: IPR011701. | 0.449 |
| NepI_4 | yajD | HMPREF0758_4744 | HMPREF0758_4747 | Transporter, major facilitator family protein; COG: COG2814; Pfam: PF07690; InterPro: IPR011701. | HNH endonuclease domain protein; Pfam: PF01844. | 0.421 |
| NepI_4 | ydeV | HMPREF0758_4744 | HMPREF0758_4743 | Transporter, major facilitator family protein; COG: COG2814; Pfam: PF07690; InterPro: IPR011701. | Carbohydrate kinase, FGGY family protein; Catalyzes the phosphorylation of autoinducer-2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3-dione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position. | 0.431 |
| NepI_4 | yeaN | HMPREF0758_4744 | HMPREF0758_2042 | Transporter, major facilitator family protein; COG: COG2814; Pfam: PF07690; InterPro: IPR011701. | Transporter, major facilitator family protein; COG: COG2807; Pfam: PF07690; InterPro: IPR011701. | 0.436 |
| NepI_4 | yeaN2 | HMPREF0758_4744 | HMPREF0758_2270 | Transporter, major facilitator family protein; COG: COG2814; Pfam: PF07690; InterPro: IPR011701. | Transporter, major facilitator family protein; COG: COG2807; Pfam: PF07690; InterPro: IPR011701. | 0.481 |
| cynX | NepI_4 | HMPREF0758_1441 | HMPREF0758_4744 | Transporter, major facilitator family protein; COG: COG2807; Pfam: PF07690; InterPro: IPR011701. | Transporter, major facilitator family protein; COG: COG2814; Pfam: PF07690; InterPro: IPR011701. | 0.449 |
| yajD | BenM_4 | HMPREF0758_4747 | HMPREF0758_4745 | HNH endonuclease domain protein; Pfam: PF01844. | Transcriptional regulator, LysR family; COG: COG0583; Pfam: PF00126; InterPro: IPR011991; Belongs to the LysR transcriptional regulatory family. | 0.525 |
| yajD | DmlR_39 | HMPREF0758_4747 | HMPREF0758_4746 | HNH endonuclease domain protein; Pfam: PF01844. | Hypothetical protein; COG: COG0583; Pfam: PF03466; InterPro: IPR005119. | 0.568 |
| yajD | NepI_4 | HMPREF0758_4747 | HMPREF0758_4744 | HNH endonuclease domain protein; Pfam: PF01844. | Transporter, major facilitator family protein; COG: COG2814; Pfam: PF07690; InterPro: IPR011701. | 0.421 |
| ydeV | NepI_4 | HMPREF0758_4743 | HMPREF0758_4744 | Carbohydrate kinase, FGGY family protein; Catalyzes the phosphorylation of autoinducer-2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3-dione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position. | Transporter, major facilitator family protein; COG: COG2814; Pfam: PF07690; InterPro: IPR011701. | 0.431 |
| yeaN | NepI_4 | HMPREF0758_2042 | HMPREF0758_4744 | Transporter, major facilitator family protein; COG: COG2807; Pfam: PF07690; InterPro: IPR011701. | Transporter, major facilitator family protein; COG: COG2814; Pfam: PF07690; InterPro: IPR011701. | 0.436 |
| yeaN2 | NepI_4 | HMPREF0758_2270 | HMPREF0758_4744 | Transporter, major facilitator family protein; COG: COG2807; Pfam: PF07690; InterPro: IPR011701. | Transporter, major facilitator family protein; COG: COG2814; Pfam: PF07690; InterPro: IPR011701. | 0.481 |