| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFE93444.1 | pgm | HMPREF0758_4877 | HMPREF0758_4874 | Hypothetical protein. | Phosphoglucomutase, alpha-D-glucose phosphate-specific; COG: COG0033; Pfam: PF02878,PF02879,PF02880,PF00408; InterPro: IPR005852. | 0.459 |
| EFE93444.1 | seqA | HMPREF0758_4877 | HMPREF0758_4875 | Hypothetical protein. | SeqA protein; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. | 0.493 |
| EFE93444.1 | ybfE | HMPREF0758_4877 | HMPREF0758_4878 | Hypothetical protein. | Ribbon-helix-helix protein, CopG family; Pfam: PF01402. | 0.468 |
| EFE93444.1 | ybfF | HMPREF0758_4877 | HMPREF0758_4876 | Hypothetical protein. | Hydrolase, alpha/beta domain protein; COG: COG0596; Pfam: PF00561; InterPro: IPR000073. | 0.773 |
| acpP | ybfF | HMPREF0758_4186 | HMPREF0758_4876 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | Hydrolase, alpha/beta domain protein; COG: COG0596; Pfam: PF00561; InterPro: IPR000073. | 0.421 |
| pgm | EFE93444.1 | HMPREF0758_4874 | HMPREF0758_4877 | Phosphoglucomutase, alpha-D-glucose phosphate-specific; COG: COG0033; Pfam: PF02878,PF02879,PF02880,PF00408; InterPro: IPR005852. | Hypothetical protein. | 0.459 |
| pgm | seqA | HMPREF0758_4874 | HMPREF0758_4875 | Phosphoglucomutase, alpha-D-glucose phosphate-specific; COG: COG0033; Pfam: PF02878,PF02879,PF02880,PF00408; InterPro: IPR005852. | SeqA protein; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. | 0.748 |
| pgm | ybfF | HMPREF0758_4874 | HMPREF0758_4876 | Phosphoglucomutase, alpha-D-glucose phosphate-specific; COG: COG0033; Pfam: PF02878,PF02879,PF02880,PF00408; InterPro: IPR005852. | Hydrolase, alpha/beta domain protein; COG: COG0596; Pfam: PF00561; InterPro: IPR000073. | 0.507 |
| seqA | EFE93444.1 | HMPREF0758_4875 | HMPREF0758_4877 | SeqA protein; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. | Hypothetical protein. | 0.493 |
| seqA | pgm | HMPREF0758_4875 | HMPREF0758_4874 | SeqA protein; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. | Phosphoglucomutase, alpha-D-glucose phosphate-specific; COG: COG0033; Pfam: PF02878,PF02879,PF02880,PF00408; InterPro: IPR005852. | 0.748 |
| seqA | ybfE | HMPREF0758_4875 | HMPREF0758_4878 | SeqA protein; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. | Ribbon-helix-helix protein, CopG family; Pfam: PF01402. | 0.716 |
| seqA | ybfF | HMPREF0758_4875 | HMPREF0758_4876 | SeqA protein; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. | Hydrolase, alpha/beta domain protein; COG: COG0596; Pfam: PF00561; InterPro: IPR000073. | 0.513 |
| ybfE | EFE93444.1 | HMPREF0758_4878 | HMPREF0758_4877 | Ribbon-helix-helix protein, CopG family; Pfam: PF01402. | Hypothetical protein. | 0.468 |
| ybfE | seqA | HMPREF0758_4878 | HMPREF0758_4875 | Ribbon-helix-helix protein, CopG family; Pfam: PF01402. | SeqA protein; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. | 0.716 |
| ybfE | ybfF | HMPREF0758_4878 | HMPREF0758_4876 | Ribbon-helix-helix protein, CopG family; Pfam: PF01402. | Hydrolase, alpha/beta domain protein; COG: COG0596; Pfam: PF00561; InterPro: IPR000073. | 0.489 |
| ybfF | EFE93444.1 | HMPREF0758_4876 | HMPREF0758_4877 | Hydrolase, alpha/beta domain protein; COG: COG0596; Pfam: PF00561; InterPro: IPR000073. | Hypothetical protein. | 0.773 |
| ybfF | acpP | HMPREF0758_4876 | HMPREF0758_4186 | Hydrolase, alpha/beta domain protein; COG: COG0596; Pfam: PF00561; InterPro: IPR000073. | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | 0.421 |
| ybfF | pgm | HMPREF0758_4876 | HMPREF0758_4874 | Hydrolase, alpha/beta domain protein; COG: COG0596; Pfam: PF00561; InterPro: IPR000073. | Phosphoglucomutase, alpha-D-glucose phosphate-specific; COG: COG0033; Pfam: PF02878,PF02879,PF02880,PF00408; InterPro: IPR005852. | 0.507 |
| ybfF | seqA | HMPREF0758_4876 | HMPREF0758_4875 | Hydrolase, alpha/beta domain protein; COG: COG0596; Pfam: PF00561; InterPro: IPR000073. | SeqA protein; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. | 0.513 |
| ybfF | ybfE | HMPREF0758_4876 | HMPREF0758_4878 | Hydrolase, alpha/beta domain protein; COG: COG0596; Pfam: PF00561; InterPro: IPR000073. | Ribbon-helix-helix protein, CopG family; Pfam: PF01402. | 0.489 |