| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| IlvM | YejL | HMPREF0758_1133 | HMPREF0758_2857 | Hypothetical protein; COG: COG3978; 2.2.1.6. | Hypothetical protein; COG: COG3082; Pfam: PF07208; InterPro: IPR009857; Belongs to the UPF0352 family. | 0.679 |
| IlvM | cpxP | HMPREF0758_1133 | HMPREF0758_1231 | Hypothetical protein; COG: COG3978; 2.2.1.6. | Periplasmic repressor CpxP; COG: COG3678; Pfam: PF07813. | 0.601 |
| IlvM | crl | HMPREF0758_1133 | HMPREF0758_0318 | Hypothetical protein; COG: COG3978; 2.2.1.6. | Transcriptional regulator Crl; Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32; Belongs to the Crl family. | 0.718 |
| IlvM | gsk | HMPREF0758_1133 | HMPREF0758_0149 | Hypothetical protein; COG: COG3978; 2.2.1.6. | Kinase, PfkB family; COG: COG0524; Pfam: PF00294; InterPro: IPR011611. | 0.683 |
| IlvM | minE | HMPREF0758_1133 | HMPREF0758_3457 | Hypothetical protein; COG: COG3978; 2.2.1.6. | Putative cell division topological specificity factor MinE; COG: COG0851; Pfam: PF03776. | 0.714 |
| IlvM | seqA | HMPREF0758_1133 | HMPREF0758_4875 | Hypothetical protein; COG: COG3978; 2.2.1.6. | SeqA protein; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. | 0.656 |
| IlvM | viaA | HMPREF0758_1133 | HMPREF0758_1320 | Hypothetical protein; COG: COG3978; 2.2.1.6. | Putative protein ViaA; COG: COG2425. | 0.676 |
| IlvM | ybfE | HMPREF0758_1133 | HMPREF0758_4878 | Hypothetical protein; COG: COG3978; 2.2.1.6. | Ribbon-helix-helix protein, CopG family; Pfam: PF01402. | 0.769 |
| IlvM | zapC | HMPREF0758_1133 | HMPREF0758_4351 | Hypothetical protein; COG: COG3978; 2.2.1.6. | Hypothetical protein; Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ. | 0.750 |
| YejL | IlvM | HMPREF0758_2857 | HMPREF0758_1133 | Hypothetical protein; COG: COG3082; Pfam: PF07208; InterPro: IPR009857; Belongs to the UPF0352 family. | Hypothetical protein; COG: COG3978; 2.2.1.6. | 0.679 |
| YejL | crl | HMPREF0758_2857 | HMPREF0758_0318 | Hypothetical protein; COG: COG3082; Pfam: PF07208; InterPro: IPR009857; Belongs to the UPF0352 family. | Transcriptional regulator Crl; Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32; Belongs to the Crl family. | 0.558 |
| YejL | seqA | HMPREF0758_2857 | HMPREF0758_4875 | Hypothetical protein; COG: COG3082; Pfam: PF07208; InterPro: IPR009857; Belongs to the UPF0352 family. | SeqA protein; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. | 0.774 |
| YejL | viaA | HMPREF0758_2857 | HMPREF0758_1320 | Hypothetical protein; COG: COG3082; Pfam: PF07208; InterPro: IPR009857; Belongs to the UPF0352 family. | Putative protein ViaA; COG: COG2425. | 0.488 |
| YejL | ybfE | HMPREF0758_2857 | HMPREF0758_4878 | Hypothetical protein; COG: COG3082; Pfam: PF07208; InterPro: IPR009857; Belongs to the UPF0352 family. | Ribbon-helix-helix protein, CopG family; Pfam: PF01402. | 0.633 |
| YejL | zapC | HMPREF0758_2857 | HMPREF0758_4351 | Hypothetical protein; COG: COG3082; Pfam: PF07208; InterPro: IPR009857; Belongs to the UPF0352 family. | Hypothetical protein; Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ. | 0.709 |
| cpxP | IlvM | HMPREF0758_1231 | HMPREF0758_1133 | Periplasmic repressor CpxP; COG: COG3678; Pfam: PF07813. | Hypothetical protein; COG: COG3978; 2.2.1.6. | 0.601 |
| cpxP | crl | HMPREF0758_1231 | HMPREF0758_0318 | Periplasmic repressor CpxP; COG: COG3678; Pfam: PF07813. | Transcriptional regulator Crl; Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32; Belongs to the Crl family. | 0.436 |
| cpxP | minE | HMPREF0758_1231 | HMPREF0758_3457 | Periplasmic repressor CpxP; COG: COG3678; Pfam: PF07813. | Putative cell division topological specificity factor MinE; COG: COG0851; Pfam: PF03776. | 0.683 |
| cpxP | viaA | HMPREF0758_1231 | HMPREF0758_1320 | Periplasmic repressor CpxP; COG: COG3678; Pfam: PF07813. | Putative protein ViaA; COG: COG2425. | 0.559 |
| cpxP | ybfE | HMPREF0758_1231 | HMPREF0758_4878 | Periplasmic repressor CpxP; COG: COG3678; Pfam: PF07813. | Ribbon-helix-helix protein, CopG family; Pfam: PF01402. | 0.570 |