| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cutC | nagA | HMPREF0758_3414 | HMPREF0758_4888 | CutC family protein; Participates in the control of copper homeostasis. Belongs to the CutC family. | N-acetylglucosamine-6-phosphate deacetylase; COG: COG1820; Pfam: PF01979; InterPro: IPR003764. | 0.499 |
| cutC | nagB | HMPREF0758_3414 | HMPREF0758_4887 | CutC family protein; Participates in the control of copper homeostasis. Belongs to the CutC family. | Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. | 0.675 |
| glmM | glmS | HMPREF0758_0808 | HMPREF0758_1337 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.957 |
| glmM | nagA | HMPREF0758_0808 | HMPREF0758_4888 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | N-acetylglucosamine-6-phosphate deacetylase; COG: COG1820; Pfam: PF01979; InterPro: IPR003764. | 0.917 |
| glmM | nagB | HMPREF0758_0808 | HMPREF0758_4887 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. | 0.923 |
| glmS | glmM | HMPREF0758_1337 | HMPREF0758_0808 | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.957 |
| glmS | mak | HMPREF0758_1337 | HMPREF0758_0250 | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | ROK family protein; COG: COG1940; Pfam: PF00480; InterPro: IPR000600. | 0.913 |
| glmS | manA | HMPREF0758_1337 | HMPREF0758_3835 | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Mannose-6-phosphate isomerase, class I; COG: COG1482; Pfam: PF01238; InterPro: IPR001250; Belongs to the mannose-6-phosphate isomerase type 1 family. | 0.918 |
| glmS | nagA | HMPREF0758_1337 | HMPREF0758_4888 | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | N-acetylglucosamine-6-phosphate deacetylase; COG: COG1820; Pfam: PF01979; InterPro: IPR003764. | 0.940 |
| glmS | nagB | HMPREF0758_1337 | HMPREF0758_4887 | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. | 0.940 |
| glmS | pgi | HMPREF0758_1337 | HMPREF0758_1693 | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Glucose-6-phosphate isomerase; COG: COG0166; Pfam: PF00342; InterPro: IPR001672; Belongs to the GPI family. | 0.938 |
| glmS | scrK-2 | HMPREF0758_1337 | HMPREF0758_1987 | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Fructokinase; COG: COG0524; Pfam: PF00294; InterPro: IPR011611; Belongs to the carbohydrate kinase PfkB family. | 0.907 |
| mak | glmS | HMPREF0758_0250 | HMPREF0758_1337 | ROK family protein; COG: COG1940; Pfam: PF00480; InterPro: IPR000600. | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.913 |
| mak | manA | HMPREF0758_0250 | HMPREF0758_3835 | ROK family protein; COG: COG1940; Pfam: PF00480; InterPro: IPR000600. | Mannose-6-phosphate isomerase, class I; COG: COG1482; Pfam: PF01238; InterPro: IPR001250; Belongs to the mannose-6-phosphate isomerase type 1 family. | 0.918 |
| mak | nagB | HMPREF0758_0250 | HMPREF0758_4887 | ROK family protein; COG: COG1940; Pfam: PF00480; InterPro: IPR000600. | Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. | 0.917 |
| mak | pgi | HMPREF0758_0250 | HMPREF0758_1693 | ROK family protein; COG: COG1940; Pfam: PF00480; InterPro: IPR000600. | Glucose-6-phosphate isomerase; COG: COG0166; Pfam: PF00342; InterPro: IPR001672; Belongs to the GPI family. | 0.916 |
| mak | scrK-2 | HMPREF0758_0250 | HMPREF0758_1987 | ROK family protein; COG: COG1940; Pfam: PF00480; InterPro: IPR000600. | Fructokinase; COG: COG0524; Pfam: PF00294; InterPro: IPR011611; Belongs to the carbohydrate kinase PfkB family. | 0.902 |
| manA | glmS | HMPREF0758_3835 | HMPREF0758_1337 | Mannose-6-phosphate isomerase, class I; COG: COG1482; Pfam: PF01238; InterPro: IPR001250; Belongs to the mannose-6-phosphate isomerase type 1 family. | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.918 |
| manA | mak | HMPREF0758_3835 | HMPREF0758_0250 | Mannose-6-phosphate isomerase, class I; COG: COG1482; Pfam: PF01238; InterPro: IPR001250; Belongs to the mannose-6-phosphate isomerase type 1 family. | ROK family protein; COG: COG1940; Pfam: PF00480; InterPro: IPR000600. | 0.918 |
| manA | nagB | HMPREF0758_3835 | HMPREF0758_4887 | Mannose-6-phosphate isomerase, class I; COG: COG1482; Pfam: PF01238; InterPro: IPR001250; Belongs to the mannose-6-phosphate isomerase type 1 family. | Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. | 0.928 |