| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EFE93262.1 | EFE95441.1 | HMPREF0758_5083 | HMPREF0758_2861 | SNF2 family N-terminal domain protein; COG: COG0553; Pfam: PF00176,PF00271; InterPro: IPR000330. | Helicase C-terminal domain protein; COG: COG1061; Pfam: PF04851,PF00271; InterPro: IPR014001. | 0.926 |
| EFE93262.1 | dnaN | HMPREF0758_5083 | HMPREF0758_1366 | SNF2 family N-terminal domain protein; COG: COG0553; Pfam: PF00176,PF00271; InterPro: IPR000330. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.793 |
| EFE93262.1 | polA | HMPREF0758_5083 | HMPREF0758_1303 | SNF2 family N-terminal domain protein; COG: COG0553; Pfam: PF00176,PF00271; InterPro: IPR000330. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.787 |
| EFE93262.1 | recA | HMPREF0758_5083 | HMPREF0758_0426 | SNF2 family N-terminal domain protein; COG: COG0553; Pfam: PF00176,PF00271; InterPro: IPR000330. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.706 |
| EFE93262.1 | recQ | HMPREF0758_5083 | HMPREF0758_1547 | SNF2 family N-terminal domain protein; COG: COG0553; Pfam: PF00176,PF00271; InterPro: IPR000330. | ATP-dependent DNA helicase RecQ; COG: COG0514; Pfam: PF00270,PF00271,PF00570; InterPro: IPR004589. | 0.726 |
| EFE93262.1 | rpoA | HMPREF0758_5083 | HMPREF0758_0937 | SNF2 family N-terminal domain protein; COG: COG0553; Pfam: PF00176,PF00271; InterPro: IPR000330. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.894 |
| EFE93262.1 | rpoB | HMPREF0758_5083 | HMPREF0758_1662 | SNF2 family N-terminal domain protein; COG: COG0553; Pfam: PF00176,PF00271; InterPro: IPR000330. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.888 |
| EFE93262.1 | rpoC | HMPREF0758_5083 | HMPREF0758_1663 | SNF2 family N-terminal domain protein; COG: COG0553; Pfam: PF00176,PF00271; InterPro: IPR000330. | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.703 |
| EFE93262.1 | rpoZ | HMPREF0758_5083 | HMPREF0758_1279 | SNF2 family N-terminal domain protein; COG: COG0553; Pfam: PF00176,PF00271; InterPro: IPR000330. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.891 |
| EFE93262.1 | udk | HMPREF0758_5083 | HMPREF0758_4577 | SNF2 family N-terminal domain protein; COG: COG0553; Pfam: PF00176,PF00271; InterPro: IPR000330. | Uridine kinase; COG: COG0572; Pfam: PF00485; InterPro: IPR000764. | 0.740 |
| EFE95441.1 | EFE93262.1 | HMPREF0758_2861 | HMPREF0758_5083 | Helicase C-terminal domain protein; COG: COG1061; Pfam: PF04851,PF00271; InterPro: IPR014001. | SNF2 family N-terminal domain protein; COG: COG0553; Pfam: PF00176,PF00271; InterPro: IPR000330. | 0.926 |
| EFE95441.1 | dnaN | HMPREF0758_2861 | HMPREF0758_1366 | Helicase C-terminal domain protein; COG: COG1061; Pfam: PF04851,PF00271; InterPro: IPR014001. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.465 |
| EFE95441.1 | polA | HMPREF0758_2861 | HMPREF0758_1303 | Helicase C-terminal domain protein; COG: COG1061; Pfam: PF04851,PF00271; InterPro: IPR014001. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.928 |
| EFE95441.1 | recA | HMPREF0758_2861 | HMPREF0758_0426 | Helicase C-terminal domain protein; COG: COG1061; Pfam: PF04851,PF00271; InterPro: IPR014001. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.459 |
| EFE95441.1 | recQ | HMPREF0758_2861 | HMPREF0758_1547 | Helicase C-terminal domain protein; COG: COG1061; Pfam: PF04851,PF00271; InterPro: IPR014001. | ATP-dependent DNA helicase RecQ; COG: COG0514; Pfam: PF00270,PF00271,PF00570; InterPro: IPR004589. | 0.466 |
| EFE95441.1 | rpoA | HMPREF0758_2861 | HMPREF0758_0937 | Helicase C-terminal domain protein; COG: COG1061; Pfam: PF04851,PF00271; InterPro: IPR014001. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.955 |
| EFE95441.1 | rpoB | HMPREF0758_2861 | HMPREF0758_1662 | Helicase C-terminal domain protein; COG: COG1061; Pfam: PF04851,PF00271; InterPro: IPR014001. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.950 |
| EFE95441.1 | rpoC | HMPREF0758_2861 | HMPREF0758_1663 | Helicase C-terminal domain protein; COG: COG1061; Pfam: PF04851,PF00271; InterPro: IPR014001. | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.815 |
| EFE95441.1 | rpoZ | HMPREF0758_2861 | HMPREF0758_1279 | Helicase C-terminal domain protein; COG: COG1061; Pfam: PF04851,PF00271; InterPro: IPR014001. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.953 |
| EFE95441.1 | udk | HMPREF0758_2861 | HMPREF0758_4577 | Helicase C-terminal domain protein; COG: COG1061; Pfam: PF04851,PF00271; InterPro: IPR014001. | Uridine kinase; COG: COG0572; Pfam: PF00485; InterPro: IPR000764. | 0.500 |