STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
guaAAHypothetical protein; Catalyzes the synthesis of GMP from XMP. (188 aa)    
Predicted Functional Partners:
guaAB
Hypothetical protein; Catalyzes the synthesis of GMP from XMP.
  
 0.999
guaB
Hypothetical protein; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
 
 
 0.969
EQB70123.1
Hypothetical protein; S4JAPL_C00075G00001; S4JAPL_00595G0001.
 
 
 0.966
surE
5'-nucleotidase surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.962
EQB70951.1
Hypothetical protein; S4JAPL_C00043G00017; S4JAPL_17306G0017; Belongs to the HAM1 NTPase family.
 
 
 0.958
EQB71258.1
Hypothetical protein; S4JAPL_C00031G00029; S4JAPL_17500G0029.
    
 0.938
purA
Hypothetical protein; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
 
  
 0.920
map
Hypothetical protein; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val); Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.
  
    0.892
EQB71876.1
Hypothetical protein; S4JAPL_C00017G00063; S4JAPL_14887G0063; Belongs to the glutamine synthetase family.
 
  
 0.886
EQB72285.1
Hypothetical protein; S4JAPL_C00010G00044; S4JAPL_17298G0044.
 
 
 0.878
Your Current Organism:
Thermoplasmatales archaeon Aplasma
NCBI taxonomy Id: 667135
Other names: T. archaeon A-plasma, Thermoplasmatales archaeon A-plasma
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.