STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaKHypothetical protein; Acts as a chaperone. (624 aa)    
Predicted Functional Partners:
dnaJ
Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, Dna [...]
 0.999
grpE
Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dep [...]
 
 0.999
rpl10e
Hypothetical protein; UNLEPL_C00002G00211; UNLEPL_17965G0211; Belongs to the universal ribosomal protein uL16 family.
  
 0.993
EQB66757.1
NifU family SUF system FeS assembly protein; UNLEPL_C00003G00314; UNLEPL_15243G0314.
  
 
 0.986
EQB67457.1
Hypothetical protein; UNLEPL_C00002G00293; UNLEPL_17965G0293; Belongs to the TCP-1 chaperonin family.
  
 
 0.968
EQB66698.1
Hypothetical protein; UNLEPL_C00003G00255; UNLEPL_15243G0255; Belongs to the TCP-1 chaperonin family.
  
 
 0.968
rpl40e
50S ribosomal protein L40E; UNLEPL_C00002G00197; UNLEPL_17965G0197; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 0.958
EQB67249.1
Hypothetical protein; UNLEPL_C00002G00085; UNLEPL_17965G0085.
  
 0.940
EQB67363.1
O-linked N-acetylglucosamine transferase; UNLEPL_C00002G00199; UNLEPL_17965G0199.
  
 0.940
EQB67452.1
Hypothetical protein; UNLEPL_C00002G00288; UNLEPL_17965G0288.
  
 0.940
Your Current Organism:
Thermoplasmatales archaeon Eplasma
NCBI taxonomy Id: 667137
Other names: T. archaeon E-plasma, Thermoplasmatales archaeon E-plasma
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