STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EQB67210.1Diphthine synthase; UNLEPL_C00002G00046; UNLEPL_17965G0046. (248 aa)    
Predicted Functional Partners:
EQB66585.1
Hypothetical protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family.
  
 0.999
EQB65809.1
Hypothetical protein; UNLEPL_C00003G00826; UNLEPL_15243G0826.
 
 
 0.999
fusA
Hypothetical protein; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
  
 
 0.985
eno
Hypothetical protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 
  0.975
EQB67213.1
Hypothetical protein; UNLEPL_C00002G00049; UNLEPL_17965G0049.
   
   0.793
EQB67212.1
Acetyltransferase; UNLEPL_C00002G00048; UNLEPL_17965G0048.
       0.702
EQB66921.1
Nucleolar protein Nop56 related protein; UNLEPL_C00003G00478; UNLEPL_15243G0478.
  
    0.682
EQB67316.1
Hypothetical protein; UNLEPL_C00002G00152; UNLEPL_17965G0152; Belongs to the MCM family.
  
     0.672
fen
Hypothetical protein; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. [...]
  
     0.668
EQB67435.1
Hypothetical protein; UNLEPL_C00002G00271; UNLEPL_17965G0271.
  
    0.658
Your Current Organism:
Thermoplasmatales archaeon Eplasma
NCBI taxonomy Id: 667137
Other names: T. archaeon E-plasma, Thermoplasmatales archaeon E-plasma
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.