STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EQB66508.1Hypothetical protein; UNLEPL_C00003G00065; UNLEPL_15243G0065. (307 aa)    
Predicted Functional Partners:
topA
Hypothetical protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA sup [...]
 
     0.970
EQB67472.1
PRC-barrel protein; UNLEPL_C00002G00308; UNLEPL_17965G0308.
  
     0.727
EQB67567.1
Hypothetical protein; UNLEPL_C00002G00403; UNLEPL_17965G0403.
  
     0.714
EQB67288.1
Hypothetical protein; UNLEPL_C00002G00124; UNLEPL_17965G0124.
  
     0.711
EQB67056.1
Type II secretion system F protein; UNLEPL_C00003G00613; UNLEPL_15243G0613.
  
     0.698
EQB67057.1
Type II secretion system F protein; UNLEPL_C00003G00614; UNLEPL_15243G0614.
  
     0.687
EQB67718.1
Hypothetical protein; UNLEPL_C00002G00554; UNLEPL_17965G0554.
  
     0.680
EQB66968.1
Hypothetical protein; UNLEPL_C00003G00525; UNLEPL_15243G0525.
  
     0.668
EQB65118.1
Hypothetical protein; UNLEPL_C00004G00061; UNLEPL_15833G0061.
  
     0.667
EQB66791.1
Hypothetical protein; UNLEPL_C00003G00348; UNLEPL_15243G0348.
  
     0.659
Your Current Organism:
Thermoplasmatales archaeon Eplasma
NCBI taxonomy Id: 667137
Other names: T. archaeon E-plasma, Thermoplasmatales archaeon E-plasma
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.