STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EQB66668.1Xanthine-guanine phosphoribosyltransferase; UNLEPL_C00003G00225; UNLEPL_15243G0225. (217 aa)    
Predicted Functional Partners:
guaB
Hypothetical protein; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.884
mtnP
Hypothetical protein; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
  
 
 0.875
EQB67693.1
Hypothetical protein; UNLEPL_C00002G00529; UNLEPL_17965G0529.
  
 
 0.807
EQB66873.1
Hypothetical protein; UNLEPL_C00003G00430; UNLEPL_15243G0430; Belongs to the HAM1 NTPase family.
  
 
  0.797
EQB67213.1
Hypothetical protein; UNLEPL_C00002G00049; UNLEPL_17965G0049.
   
 
  0.782
EQB67474.1
Hypothetical protein; UNLEPL_C00002G00310; UNLEPL_17965G0310.
    
  0.782
purA
Hypothetical protein; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
    
 0.747
EQB66480.1
Hypothetical protein; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
       0.705
EQB65119.1
Hypothetical protein; UNLEPL_C00004G00062; UNLEPL_15833G0062; Belongs to the OMP decarboxylase family.
    
 0.688
EQB67495.1
Nicotinamidase-like protein amidase; UNLEPL_C00002G00331; UNLEPL_17965G0331.
  
  
  0.618
Your Current Organism:
Thermoplasmatales archaeon Eplasma
NCBI taxonomy Id: 667137
Other names: T. archaeon E-plasma, Thermoplasmatales archaeon E-plasma
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