| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EQB66552.1 | EQB66761.1 | AMDU2_EPLC00006G0109 | AMDU2_EPLC00006G0318 | Hypothetical protein; UNLEPL_C00003G00109; UNLEPL_15243G0109. | Hypothetical protein; UNLEPL_C00003G00318; UNLEPL_15243G0318. | 0.947 |
| EQB66552.1 | EQB67381.1 | AMDU2_EPLC00006G0109 | AMDU2_EPLC00005G0217 | Hypothetical protein; UNLEPL_C00003G00109; UNLEPL_15243G0109. | Hypothetical protein; UNLEPL_C00002G00217; UNLEPL_17965G0217. | 0.672 |
| EQB66552.1 | EQB67585.1 | AMDU2_EPLC00006G0109 | AMDU2_EPLC00005G0421 | Hypothetical protein; UNLEPL_C00003G00109; UNLEPL_15243G0109. | 6-pyruvoyl-tetrahydropterin synthase; UNLEPL_C00002G00421; UNLEPL_17965G0421. | 0.766 |
| EQB66552.1 | mptA | AMDU2_EPLC00006G0109 | AMDU2_EPLC00006G0690 | Hypothetical protein; UNLEPL_C00003G00109; UNLEPL_15243G0109. | Hypothetical protein; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. | 0.573 |
| EQB66761.1 | EQB66552.1 | AMDU2_EPLC00006G0318 | AMDU2_EPLC00006G0109 | Hypothetical protein; UNLEPL_C00003G00318; UNLEPL_15243G0318. | Hypothetical protein; UNLEPL_C00003G00109; UNLEPL_15243G0109. | 0.947 |
| EQB66761.1 | EQB67381.1 | AMDU2_EPLC00006G0318 | AMDU2_EPLC00005G0217 | Hypothetical protein; UNLEPL_C00003G00318; UNLEPL_15243G0318. | Hypothetical protein; UNLEPL_C00002G00217; UNLEPL_17965G0217. | 0.994 |
| EQB66761.1 | EQB67585.1 | AMDU2_EPLC00006G0318 | AMDU2_EPLC00005G0421 | Hypothetical protein; UNLEPL_C00003G00318; UNLEPL_15243G0318. | 6-pyruvoyl-tetrahydropterin synthase; UNLEPL_C00002G00421; UNLEPL_17965G0421. | 0.507 |
| EQB66761.1 | mptA | AMDU2_EPLC00006G0318 | AMDU2_EPLC00006G0690 | Hypothetical protein; UNLEPL_C00003G00318; UNLEPL_15243G0318. | Hypothetical protein; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. | 0.679 |
| EQB66984.1 | mptA | AMDU2_EPLC00006G0541 | AMDU2_EPLC00006G0690 | Hypothetical protein; UNLEPL_C00003G00541; UNLEPL_15243G0541; Belongs to the pyruvate kinase family. | Hypothetical protein; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. | 0.927 |
| EQB66984.1 | ndk | AMDU2_EPLC00006G0541 | AMDU2_EPLC00005G0253 | Hypothetical protein; UNLEPL_C00003G00541; UNLEPL_15243G0541; Belongs to the pyruvate kinase family. | Hypothetical protein; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | 0.918 |
| EQB67135.1 | mptA | AMDU2_EPLC00006G0692 | AMDU2_EPLC00006G0690 | Hypothetical protein; UNLEPL_C00003G00692; UNLEPL_15243G0692. | Hypothetical protein; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. | 0.701 |
| EQB67135.1 | pfdB | AMDU2_EPLC00006G0692 | AMDU2_EPLC00006G0691 | Hypothetical protein; UNLEPL_C00003G00692; UNLEPL_15243G0692. | Hypothetical protein; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. | 0.701 |
| EQB67381.1 | EQB66552.1 | AMDU2_EPLC00005G0217 | AMDU2_EPLC00006G0109 | Hypothetical protein; UNLEPL_C00002G00217; UNLEPL_17965G0217. | Hypothetical protein; UNLEPL_C00003G00109; UNLEPL_15243G0109. | 0.672 |
| EQB67381.1 | EQB66761.1 | AMDU2_EPLC00005G0217 | AMDU2_EPLC00006G0318 | Hypothetical protein; UNLEPL_C00002G00217; UNLEPL_17965G0217. | Hypothetical protein; UNLEPL_C00003G00318; UNLEPL_15243G0318. | 0.994 |
| EQB67381.1 | mptA | AMDU2_EPLC00005G0217 | AMDU2_EPLC00006G0690 | Hypothetical protein; UNLEPL_C00002G00217; UNLEPL_17965G0217. | Hypothetical protein; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. | 0.549 |
| EQB67585.1 | EQB66552.1 | AMDU2_EPLC00005G0421 | AMDU2_EPLC00006G0109 | 6-pyruvoyl-tetrahydropterin synthase; UNLEPL_C00002G00421; UNLEPL_17965G0421. | Hypothetical protein; UNLEPL_C00003G00109; UNLEPL_15243G0109. | 0.766 |
| EQB67585.1 | EQB66761.1 | AMDU2_EPLC00005G0421 | AMDU2_EPLC00006G0318 | 6-pyruvoyl-tetrahydropterin synthase; UNLEPL_C00002G00421; UNLEPL_17965G0421. | Hypothetical protein; UNLEPL_C00003G00318; UNLEPL_15243G0318. | 0.507 |
| EQB67585.1 | EQB67606.1 | AMDU2_EPLC00005G0421 | AMDU2_EPLC00005G0442 | 6-pyruvoyl-tetrahydropterin synthase; UNLEPL_C00002G00421; UNLEPL_17965G0421. | Hypothetical protein; UNLEPL_C00002G00442; UNLEPL_17965G0442. | 0.428 |
| EQB67585.1 | mptA | AMDU2_EPLC00005G0421 | AMDU2_EPLC00006G0690 | 6-pyruvoyl-tetrahydropterin synthase; UNLEPL_C00002G00421; UNLEPL_17965G0421. | Hypothetical protein; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. | 0.917 |
| EQB67585.1 | ribA | AMDU2_EPLC00005G0421 | AMDU2_EPLC00006G0606 | 6-pyruvoyl-tetrahydropterin synthase; UNLEPL_C00002G00421; UNLEPL_17965G0421. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.422 |