STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SARC_14452Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (271 aa)    
Predicted Functional Partners:
SARC_11358
TFIIE domain-containing protein.
   
 0.997
SARC_12280
Ssl1 domain-containing protein.
   
 0.995
SARC_05854
TFIIF_beta domain-containing protein.
   
 0.995
SARC_05635
TFIIB-type domain-containing protein.
    
 0.994
SARC_02235
Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.
   
 0.994
SARC_12642
General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.
    
 0.993
SARC_11483
Cyclin_C_2 domain-containing protein.
    
 0.993
SARC_04897
TATA-box-binding protein 2.
    
 0.993
SARC_00541
Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.
   
 0.993
SARC_09428
RNA polymerase Rpb3/Rpb11 dimerization domain-containing protein.
    
 0.990
Your Current Organism:
Sphaeroforma arctica
NCBI taxonomy Id: 667725
Other names: S. arctica JP610, Sphaeroforma arctica JP610
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.