STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SARC_12476GMP synthase. (603 aa)    
Predicted Functional Partners:
SARC_11289
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
 
 0.959
SARC_00428
GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
  
 0.945
SARC_05115
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.
  
 0.929
SARC_02497
Uncharacterized protein; Belongs to the peptidase C19 family.
   
 
 0.926
SARC_16190
Pribosyltran domain-containing protein.
  
 0.916
SARC_00778
Adenine phosphoribosyltransferase.
  
 0.916
SARC_04293
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Belongs to the HisA/HisF family.
  
 
 0.851
SARC_10484
GatB_Yqey domain-containing protein.
  
 
 0.836
SARC_10485
GatB_N domain-containing protein.
  
 
 0.836
SARC_04295
Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
 0.835
Your Current Organism:
Sphaeroforma arctica
NCBI taxonomy Id: 667725
Other names: S. arctica JP610, Sphaeroforma arctica JP610
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.