STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SARC_11125DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (171 aa)    
Predicted Functional Partners:
SARC_07559
DNA_pol_E_B domain-containing protein.
   
 0.962
SARC_09779
DNA helicase; Belongs to the MCM family.
   
 0.953
SARC_04505
DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family.
   
 0.943
SARC_09190
Uncharacterized protein.
   
 0.927
SARC_01451
DNA primase; Belongs to the eukaryotic-type primase small subunit family.
   
 0.908
SARC_07062
Uncharacterized protein.
   
 0.907
SARC_17040
Uncharacterized protein.
   
 0.902
SARC_01519
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 0.899
SARC_15275
DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.
 
  
  0.897
SARC_08985
DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.
 
  
  0.894
Your Current Organism:
Sphaeroforma arctica
NCBI taxonomy Id: 667725
Other names: S. arctica JP610, Sphaeroforma arctica JP610
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.