SARC_10927 protein (Sphaeroforma arctica) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

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Score

SARC_10927

ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (439 aa)

Predicted Functional Partners:

SARC_07044

0.928

SARC_00926

0.891

SARC_04109

0.859

SARC_12517

0.833

SARC_14650

0.822

SARC_10611

0.822

SARC_03379

0.822

SARC_01829

0.822

SARC_12582

0.816

SARC_04296

0.768

Your Current Organism:

Sphaeroforma arctica

NCBI taxonomy Id: 667725
Other names: S. arctica JP610, Sphaeroforma arctica JP610

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SARC_00926	SARC_01829	A0A0L0GDE0	A0A0L0GAT3	Triosephosphate isomerase.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.821
SARC_00926	SARC_03379	A0A0L0GDE0	A0A0L0G5W1	Triosephosphate isomerase.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.821
SARC_00926	SARC_04109	A0A0L0GDE0	A0A0L0G609	Triosephosphate isomerase.	Enolase.	0.993
SARC_00926	SARC_04296	A0A0L0GDE0	A0A0L0G2Z8	Triosephosphate isomerase.	ADH_zinc_N domain-containing protein.	0.839
SARC_00926	SARC_07044	A0A0L0GDE0	A0A0L0FUT1	Triosephosphate isomerase.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.988
SARC_00926	SARC_10611	A0A0L0GDE0	A0A0L0FJE0	Triosephosphate isomerase.	Phosphoglycerate kinase.	0.998
SARC_00926	SARC_10927	A0A0L0GDE0	A0A0L0FIL4	Triosephosphate isomerase.	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.	0.891
SARC_00926	SARC_12517	A0A0L0GDE0	A0A0L0FDV8	Triosephosphate isomerase.	Uncharacterized protein.	0.989
SARC_00926	SARC_12582	A0A0L0GDE0	A0A0L0FEH1	Triosephosphate isomerase.	Fructose-bisphosphate aldolase class 2.	0.989
SARC_00926	SARC_14650	A0A0L0GDE0	A0A0L0F7U5	Triosephosphate isomerase.	Pyruvate kinase, barrel domain-containing protein.	0.821
SARC_01829	SARC_00926	A0A0L0GAT3	A0A0L0GDE0	Pyruvate kinase; Belongs to the pyruvate kinase family.	Triosephosphate isomerase.	0.821
SARC_01829	SARC_04109	A0A0L0GAT3	A0A0L0G609	Pyruvate kinase; Belongs to the pyruvate kinase family.	Enolase.	0.933
SARC_01829	SARC_04296	A0A0L0GAT3	A0A0L0G2Z8	Pyruvate kinase; Belongs to the pyruvate kinase family.	ADH_zinc_N domain-containing protein.	0.740
SARC_01829	SARC_07044	A0A0L0GAT3	A0A0L0FUT1	Pyruvate kinase; Belongs to the pyruvate kinase family.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.944
SARC_01829	SARC_10611	A0A0L0GAT3	A0A0L0FJE0	Pyruvate kinase; Belongs to the pyruvate kinase family.	Phosphoglycerate kinase.	0.920
SARC_01829	SARC_10927	A0A0L0GAT3	A0A0L0FIL4	Pyruvate kinase; Belongs to the pyruvate kinase family.	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.	0.822
SARC_01829	SARC_12517	A0A0L0GAT3	A0A0L0FDV8	Pyruvate kinase; Belongs to the pyruvate kinase family.	Uncharacterized protein.	0.923
SARC_01829	SARC_12582	A0A0L0GAT3	A0A0L0FEH1	Pyruvate kinase; Belongs to the pyruvate kinase family.	Fructose-bisphosphate aldolase class 2.	0.884
SARC_03379	SARC_00926	A0A0L0G5W1	A0A0L0GDE0	Pyruvate kinase; Belongs to the pyruvate kinase family.	Triosephosphate isomerase.	0.821
SARC_03379	SARC_04109	A0A0L0G5W1	A0A0L0G609	Pyruvate kinase; Belongs to the pyruvate kinase family.	Enolase.	0.933

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Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

25

PPI enrichment p-value:

9.09e-08

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

11 of 128

1.69

4.18

7.28e-16

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0019843

rRNA binding

11 of 44

2.15

7.64

8.20e-21

GO:0003735

Structural constituent of ribosome

11 of 57

2.04

6.81

5.26e-20

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

11 of 60

2.01

6.72

3.27e-20

GO:0015935

Small ribosomal subunit

3 of 8

2.33

2.45

1.91e-05

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:37185344

(2023) Independent origins and evolution of the secondary replicons of the class Gammaproteobacteria.

7 of 31

2.11

4.47

8.07e-11

PMID:28083017

(2016) Distribution of Hydrogenases in Cyanobacteria: A Phylum-Wide Genomic Survey.

6 of 20

2.23

4.29

9.18e-10

PMID:26096579

(2015) Neutral red-mediated microbial electrosynthesis by Escherichia coli, Klebsiella pneumoniae, and Zymomonas mobilis.

5 of 49

1.76

2.2

8.48e-06

PMID:37991636

(2023) De novo assembly and comparative genome analysis for polyhydroxyalkanoates-producing Bacillus sp. BNPI-92 strain.

3 of 36

1.67

0.93

0.0127

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:169

Ribosome

11 of 31

2.3

8.83

4.54e-22

CL:209

Small ribosomal subunit, and Ribosome

5 of 11

2.41

4.38

1.92e-09

CL:172

rRNA-binding

5 of 16

2.25

3.92

8.47e-09

CL:211

Small ribosomal subunit, and Ribosomal protein S13-like, H2TH

4 of 5

2.65

3.89

4.47e-08

CL:174

rRNA-binding

4 of 11

2.31

3.21

4.60e-07

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

reh03010

Ribosome

11 of 55

2.05

7.06

1.00e-20

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

10 of 52

2.04

6.21

1.65e-17

GOCC:0015935

Small ribosomal subunit

6 of 13

2.42

5.42

8.57e-12

GOCC:0044391

Ribosomal subunit

7 of 27

2.17

5.17

2.04e-12

GOCC:0022626

Cytosolic ribosome

5 of 21

2.13

3.68

1.42e-08

GOCC:0022627

Cytosolic small ribosomal subunit

4 of 9

2.4

3.53

1.25e-07

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0699

rRNA-binding

11 of 40

2.19

8.13

8.94e-22

KW-0689

Ribosomal protein

11 of 55

2.05

7.06

1.01e-20

KW-0820

tRNA-binding

2 of 17

1.82

0.84

0.0239

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