STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SARC_054303-isopropylmalate dehydratase. (750 aa)    
Predicted Functional Partners:
SARC_11148
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 0.997
SARC_11908
2-isopropylmalate synthase.
 
 0.983
SARC_07755
Homoisocitrate dehydrogenase.
 
 0.980
SARC_02566
Dihydroxy-acid dehydratase.
 
 
 0.978
SARC_01886
ACT domain-containing protein.
  
  
 0.950
SARC_15526
Saccharop_dh_N domain-containing protein.
  
 
 0.938
SARC_13072
Pyruvate carboxyltransferase domain-containing protein.
  
 
 0.938
SARC_13055
Hydroxymethylglutaryl-CoA lyase, mitochondrial.
  
 
 0.935
SARC_07055
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
  
 
 0.867
SARC_11426
Malate synthase G.
  
 
 0.855
Your Current Organism:
Sphaeroforma arctica
NCBI taxonomy Id: 667725
Other names: S. arctica JP610, Sphaeroforma arctica JP610
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