acsA protein (Methanobrevibacter oralis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

acsA

Acetyl-coenzyme A synthetase. (555 aa)

Predicted Functional Partners:

KZX13384.1

0.995

pcaF

0.995

sucD_1

0.990

korA_1

0.977

korB_2

0.976

rsxB_3

0.974

aldHT

0.973

accC

0.971

sucC

0.970

porB

0.969

Your Current Organism:

Methanobrevibacter oralis

NCBI taxonomy Id: 66851
Other names: DSM 7256, M. oralis, strain ZR

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KZX13384.1	acsA	MBORA_06820	MBORA_06830	DNA-binding transcriptional repressor PuuR.	Acetyl-coenzyme A synthetase.	0.995
KZX13384.1	korA_1	MBORA_06820	MBORA_05610	DNA-binding transcriptional repressor PuuR.	2-oxoglutarate oxidoreductase subunit KorA.	0.429
KZX13384.1	korB_2	MBORA_06820	MBORA_06860	DNA-binding transcriptional repressor PuuR.	2-oxoglutarate oxidoreductase subunit KorB.	0.941
KZX13384.1	rsxB_3	MBORA_06820	MBORA_06840	DNA-binding transcriptional repressor PuuR.	Electron transport complex subunit RsxB.	0.955
accC	acsA	MBORA_16930	MBORA_06830	Biotin carboxylase.	Acetyl-coenzyme A synthetase.	0.971
accC	aldHT	MBORA_16930	MBORA_11670	Biotin carboxylase.	Aldehyde dehydrogenase, thermostable.	0.761
accC	korA_1	MBORA_16930	MBORA_05610	Biotin carboxylase.	2-oxoglutarate oxidoreductase subunit KorA.	0.962
accC	pcaF	MBORA_16930	MBORA_09420	Biotin carboxylase.	beta-ketoadipyl-CoA thiolase.	0.787
accC	porB	MBORA_16930	MBORA_15000	Biotin carboxylase.	Pyruvate synthase subunit PorB.	0.958
accC	rsxB_3	MBORA_16930	MBORA_06840	Biotin carboxylase.	Electron transport complex subunit RsxB.	0.970
accC	sucC	MBORA_16930	MBORA_05580	Biotin carboxylase.	succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.773
accC	sucD_1	MBORA_16930	MBORA_08950	Biotin carboxylase.	succinyl-CoA ligase [ADP-forming] subunit alpha.	0.960
acsA	KZX13384.1	MBORA_06830	MBORA_06820	Acetyl-coenzyme A synthetase.	DNA-binding transcriptional repressor PuuR.	0.995
acsA	accC	MBORA_06830	MBORA_16930	Acetyl-coenzyme A synthetase.	Biotin carboxylase.	0.971
acsA	aldHT	MBORA_06830	MBORA_11670	Acetyl-coenzyme A synthetase.	Aldehyde dehydrogenase, thermostable.	0.973
acsA	korA_1	MBORA_06830	MBORA_05610	Acetyl-coenzyme A synthetase.	2-oxoglutarate oxidoreductase subunit KorA.	0.977
acsA	korB_2	MBORA_06830	MBORA_06860	Acetyl-coenzyme A synthetase.	2-oxoglutarate oxidoreductase subunit KorB.	0.976
acsA	pcaF	MBORA_06830	MBORA_09420	Acetyl-coenzyme A synthetase.	beta-ketoadipyl-CoA thiolase.	0.995
acsA	porB	MBORA_06830	MBORA_15000	Acetyl-coenzyme A synthetase.	Pyruvate synthase subunit PorB.	0.969
acsA	rsxB_3	MBORA_06830	MBORA_06840	Acetyl-coenzyme A synthetase.	Electron transport complex subunit RsxB.	0.974