STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ypdFAminopeptidase YpdF; Belongs to the peptidase M24B family. (340 aa)    
Predicted Functional Partners:
guaB_1
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
   0.841
tarI
Putative ribitol-5-phosphate cytidylyltransferase.
  
 
 0.794
KZX10182.1
RIO1 family protein.
    
 0.747
KZX13341.1
Aspartoacylase.
    
 0.697
hisC
Histidinol-phosphate aminotransferase.
    
 0.695
nasB
Assimilatory nitrate reductase electron transfer subunit.
 
 
 0.677
map
Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
  
  
 0.674
gatA
glutamyl-tRNA(Gln) amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).
   
 
 0.672
hrb
High molecular weight rubredoxin.
  
  
 0.646
cysE
Serine acetyltransferase.
     
 0.625
Your Current Organism:
Methanobrevibacter oralis
NCBI taxonomy Id: 66851
Other names: DSM 7256, M. oralis, strain ZR
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.