STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
C7M84_010512Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (79 aa)    
Predicted Functional Partners:
C7M84_004819
Adenylyl cyclase-associated protein; Belongs to the CAP family.
   
 0.801
C7M84_008669
Actin; Belongs to the actin family.
   
 0.722
C7M84_014722
Cofilin/actin-depolymerizing factor; Belongs to the actin-binding proteins ADF family.
   
 0.714
C7M84_015732
FH2 domain-containing protein.
    
 0.664
C7M84_003851
Small ubiquitin-related modifier.
   
 
 0.649
C7M84_010623
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
   
 0.643
C7M84_000248
Uncharacterized protein.
   
 0.634
C7M84_000247
Sprouty-related, EVH1 domain-containing protein 2.
   
 0.634
C7M84_017379
Putative unhealthy ribosome biogenesis protein 2-like.
   
 0.626
C7M84_023228
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
   
 
 0.596
Your Current Organism:
Penaeus vannamei
NCBI taxonomy Id: 6689
Other names: Litopenaeus vannamei, P. vannamei, Pacific white shrimp, Penaeus (Litopenaeus) vannamei, Penaeus sp. AT-2008, white Pacific shrimp, white shrimp
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