| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMF96222.1 | AMF96223.1 | AL538_00035 | AL538_00040 | Anti-anti-sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.665 |
| AMF96223.1 | AMF96222.1 | AL538_00040 | AL538_00035 | ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Anti-anti-sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.665 |
| AMF96223.1 | AMF96827.1 | AL538_00040 | AL538_03325 | ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.852 |
| AMF96223.1 | AMG00278.1 | AL538_00040 | AL538_21545 | ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.896 |
| AMF96223.1 | adk | AL538_00040 | AL538_13630 | ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.724 |
| AMF96223.1 | cca | AL538_00040 | AL538_11420 | ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2',3'-cyclic phosphodiesterase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. | 0.864 |
| AMF96223.1 | dnaN | AL538_00040 | AL538_09695 | ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.948 |
| AMF96223.1 | holB | AL538_00040 | AL538_03865 | ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit delta; Catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.711 |
| AMF96223.1 | polA | AL538_00040 | AL538_10135 | ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.952 |
| AMF96223.1 | xth | AL538_00040 | AL538_14695 | ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.719 |
| AMF96223.1 | ygdG | AL538_00040 | AL538_12940 | ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Protein Xni; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. | 0.785 |
| AMF96827.1 | AMF96223.1 | AL538_03325 | AL538_00040 | Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.852 |
| AMF96827.1 | AMG00278.1 | AL538_03325 | AL538_21545 | Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.881 |
| AMF96827.1 | dnaN | AL538_03325 | AL538_09695 | Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.967 |
| AMF96827.1 | holB | AL538_03325 | AL538_03865 | Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit delta; Catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.901 |
| AMF96827.1 | polA | AL538_03325 | AL538_10135 | Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.904 |
| AMF96827.1 | xth | AL538_03325 | AL538_14695 | Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology. | Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.561 |
| AMF96827.1 | ygdG | AL538_03325 | AL538_12940 | Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology. | Protein Xni; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. | 0.663 |
| AMG00278.1 | AMF96223.1 | AL538_21545 | AL538_00040 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.896 |
| AMG00278.1 | AMF96827.1 | AL538_21545 | AL538_03325 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.881 |