STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMF96842.1Amino acid:proton symporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (419 aa)    
Predicted Functional Partners:
sdhD
Succinate dehydrogenase; Membrane-anchoring subunit of succinate dehydrogenase (SDH).
   
  
 0.532
luxN
Hybrid sensor histidine kinase/response regulator; At low cell density, in the absence of AI-1 (autoinducer 1), LuxN has a kinase activity and autophosphorylates on His-471. The phosphoryl group is then transferred on Asp-771 of the response regulator domain. The phosphoryl group is transferred to LuxU, and ultimately to LuxO. At high cell density, in the presence of AI-1, the kinase activity is inactivated, and the response regulator domain has a phosphatase activity. LuxN phosphatase acts on itself. As LuxU could function to establish an equilibrium between the aspartyl-phosphate of [...]
     
 0.527
luxM
Acyl-homoserine-lactone synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.466
trpB
Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
       0.458
trpA
Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
       0.458
trpC
Bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpC family.
       0.448
AMF97748.1
Hybrid sensor histidine kinase/response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.414
AMF99019.1
Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
  
 0.405
Your Current Organism:
Vibrio harveyi
NCBI taxonomy Id: 669
Other names: ATCC 14126, Achromobacter harveyi, Beneckea harveyi, Beneckea neptuna, CAIM 513, CCUG 28584, CECT 525, CIP 103192, DSM 19623, IFO 15634, LMG 4044, LMG:4044, Lucibacterium harveyi, NBRC 15634, NCCB 80033, NCTC 12970, Photobacterium harveyi, Pseudomonas harveyi, V. harveyi, Vibrio carchariae, Vibrio sp. HENC-01, Vibrio sp. HENC-02, Vibrio sp. PG 001, Vibrio sp. PG 002, Vibrio sp. PG 006, Vibrio sp. PG 007, Vibrio trachuri
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