| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMF96849.1 | ispZ | AL538_03435 | AL538_03420 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Septation protein A; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family. | 0.439 |
| AMF96849.1 | yciA | AL538_03435 | AL538_03425 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | acyl-CoA thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.568 |
| AMF96849.1 | yciI | AL538_03435 | AL538_03430 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | BolA family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.804 |
| AMF97864.1 | lptA | AL538_09150 | AL538_07360 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Lipopolysaccharide transport periplasmic protein LptA; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm. | 0.547 |
| AMF97864.1 | yciI | AL538_09150 | AL538_03430 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | BolA family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.537 |
| AMF98607.1 | yciI | AL538_13280 | AL538_03430 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | BolA family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.429 |
| hflD | lptA | AL538_15765 | AL538_07360 | HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis; Derived by automated computational analysis using gene prediction method: Protein Homology. | Lipopolysaccharide transport periplasmic protein LptA; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm. | 0.418 |
| hflD | yciI | AL538_15765 | AL538_03430 | HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis; Derived by automated computational analysis using gene prediction method: Protein Homology. | BolA family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.407 |
| hisE | map | AL538_15835 | AL538_05480 | Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase; Catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the PRA-CH family. | Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | 0.904 |
| hisE | tatA | AL538_15835 | AL538_10105 | Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase; Catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the PRA-CH family. | Preprotein translocase subunit SecA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.624 |
| hisE | yciI | AL538_15835 | AL538_03430 | Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase; Catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the PRA-CH family. | BolA family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.535 |
| ispZ | AMF96849.1 | AL538_03420 | AL538_03435 | Septation protein A; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.439 |
| ispZ | yciA | AL538_03420 | AL538_03425 | Septation protein A; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family. | acyl-CoA thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.578 |
| ispZ | yciI | AL538_03420 | AL538_03430 | Septation protein A; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family. | BolA family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.439 |
| lptA | AMF97864.1 | AL538_07360 | AL538_09150 | Lipopolysaccharide transport periplasmic protein LptA; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm. | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.547 |
| lptA | hflD | AL538_07360 | AL538_15765 | Lipopolysaccharide transport periplasmic protein LptA; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm. | HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.418 |
| lptA | yciI | AL538_07360 | AL538_03430 | Lipopolysaccharide transport periplasmic protein LptA; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm. | BolA family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.665 |
| map | hisE | AL538_05480 | AL538_15835 | Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase; Catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the PRA-CH family. | 0.904 |
| map | yciI | AL538_05480 | AL538_03430 | Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | BolA family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.405 |
| tatA | hisE | AL538_10105 | AL538_15835 | Preprotein translocase subunit SecA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase; Catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the PRA-CH family. | 0.624 |