| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMF97011.1 | hflB | AL538_04285 | AL538_06215 | DNA topoisomerase III; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.457 |
| AMF97011.1 | topA | AL538_04285 | AL538_14790 | DNA topoisomerase III; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA topoisomerase I subunit omega; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus rem [...] | 0.499 |
| AMF97011.1 | yhbY | AL538_04285 | AL538_06225 | DNA topoisomerase III; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA binding protein found associated to pre-50S subunit of the ribosome; putative role in ribosome assembly; necessary for optimal growth but not cell viability; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.516 |
| AMF97900.1 | AMG00407.1 | AL538_09410 | AL538_22230 | Shikimate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nicotinate-nicotinamide nucleotide adenylyltransferase; Catalyzes the formation of deamido-NAD(+) from nicotinate ribonucleotide and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.853 |
| AMF97900.1 | rsfS | AL538_09410 | AL538_13080 | Shikimate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Iojap protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.490 |
| AMF97900.1 | yhbY | AL538_09410 | AL538_06225 | Shikimate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA binding protein found associated to pre-50S subunit of the ribosome; putative role in ribosome assembly; necessary for optimal growth but not cell viability; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.596 |
| AMF98851.1 | yhbY | AL538_14600 | AL538_06225 | DNA internalization-related competence protein ComEC/Rec2; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA binding protein found associated to pre-50S subunit of the ribosome; putative role in ribosome assembly; necessary for optimal growth but not cell viability; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.445 |
| AMF98883.1 | yhbY | AL538_14760 | AL538_06225 | Translation initiation factor IF-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA binding protein found associated to pre-50S subunit of the ribosome; putative role in ribosome assembly; necessary for optimal growth but not cell viability; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.528 |
| AMG00407.1 | AMF97900.1 | AL538_22230 | AL538_09410 | Nicotinate-nicotinamide nucleotide adenylyltransferase; Catalyzes the formation of deamido-NAD(+) from nicotinate ribonucleotide and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. | Shikimate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.853 |
| AMG00407.1 | rsfS | AL538_22230 | AL538_13080 | Nicotinate-nicotinamide nucleotide adenylyltransferase; Catalyzes the formation of deamido-NAD(+) from nicotinate ribonucleotide and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. | Iojap protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.843 |
| AMG00407.1 | yhbY | AL538_22230 | AL538_06225 | Nicotinate-nicotinamide nucleotide adenylyltransferase; Catalyzes the formation of deamido-NAD(+) from nicotinate ribonucleotide and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA binding protein found associated to pre-50S subunit of the ribosome; putative role in ribosome assembly; necessary for optimal growth but not cell viability; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.856 |
| hflB | AMF97011.1 | AL538_06215 | AL538_04285 | ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | DNA topoisomerase III; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.457 |
| hflB | rrmJ | AL538_06215 | AL538_06220 | ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 23S rRNA methyltransferase; Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.929 |
| hflB | topA | AL538_06215 | AL538_14790 | ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | DNA topoisomerase I subunit omega; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus rem [...] | 0.457 |
| hflB | yhbY | AL538_06215 | AL538_06225 | ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | RNA binding protein found associated to pre-50S subunit of the ribosome; putative role in ribosome assembly; necessary for optimal growth but not cell viability; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.455 |
| mreC | yhbY | AL538_07465 | AL538_06225 | Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape. | RNA binding protein found associated to pre-50S subunit of the ribosome; putative role in ribosome assembly; necessary for optimal growth but not cell viability; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.442 |
| rrmJ | hflB | AL538_06220 | AL538_06215 | 23S rRNA methyltransferase; Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.929 |
| rrmJ | rsfS | AL538_06220 | AL538_13080 | 23S rRNA methyltransferase; Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | Iojap protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.657 |
| rrmJ | yhbY | AL538_06220 | AL538_06225 | 23S rRNA methyltransferase; Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA binding protein found associated to pre-50S subunit of the ribosome; putative role in ribosome assembly; necessary for optimal growth but not cell viability; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.606 |
| rsfS | AMF97900.1 | AL538_13080 | AL538_09410 | Iojap protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | Shikimate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.490 |