| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMF97900.1 | AMG00407.1 | AL538_09410 | AL538_22230 | Shikimate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nicotinate-nicotinamide nucleotide adenylyltransferase; Catalyzes the formation of deamido-NAD(+) from nicotinate ribonucleotide and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.834 |
| AMF97900.1 | rsfS | AL538_09410 | AL538_13080 | Shikimate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Iojap protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.522 |
| AMF97900.1 | yhbY | AL538_09410 | AL538_06225 | Shikimate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA binding protein found associated to pre-50S subunit of the ribosome; putative role in ribosome assembly; necessary for optimal growth but not cell viability; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.558 |
| AMF98883.1 | rplK | AL538_14760 | AL538_08675 | Translation initiation factor IF-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S ribosomal protein L11; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uL11 family. | 0.958 |
| AMF98883.1 | secG | AL538_14760 | AL538_06200 | Translation initiation factor IF-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.787 |
| AMF98883.1 | yhbY | AL538_14760 | AL538_06225 | Translation initiation factor IF-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA binding protein found associated to pre-50S subunit of the ribosome; putative role in ribosome assembly; necessary for optimal growth but not cell viability; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.524 |
| AMG00407.1 | AMF97900.1 | AL538_22230 | AL538_09410 | Nicotinate-nicotinamide nucleotide adenylyltransferase; Catalyzes the formation of deamido-NAD(+) from nicotinate ribonucleotide and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. | Shikimate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.834 |
| AMG00407.1 | rsfS | AL538_22230 | AL538_13080 | Nicotinate-nicotinamide nucleotide adenylyltransferase; Catalyzes the formation of deamido-NAD(+) from nicotinate ribonucleotide and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. | Iojap protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.856 |
| AMG00407.1 | yhbY | AL538_22230 | AL538_06225 | Nicotinate-nicotinamide nucleotide adenylyltransferase; Catalyzes the formation of deamido-NAD(+) from nicotinate ribonucleotide and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA binding protein found associated to pre-50S subunit of the ribosome; putative role in ribosome assembly; necessary for optimal growth but not cell viability; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.877 |
| folP | hflB | AL538_06210 | AL538_06215 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.855 |
| folP | rrmJ | AL538_06210 | AL538_06220 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 23S rRNA methyltransferase; Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.701 |
| folP | secG | AL538_06210 | AL538_06200 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.688 |
| folP | yhbY | AL538_06210 | AL538_06225 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | RNA binding protein found associated to pre-50S subunit of the ribosome; putative role in ribosome assembly; necessary for optimal growth but not cell viability; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.617 |
| hflB | folP | AL538_06215 | AL538_06210 | ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.855 |
| hflB | rplK | AL538_06215 | AL538_08675 | ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 50S ribosomal protein L11; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uL11 family. | 0.781 |
| hflB | rrmJ | AL538_06215 | AL538_06220 | ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 23S rRNA methyltransferase; Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.973 |
| hflB | secG | AL538_06215 | AL538_06200 | ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.724 |
| hflB | yhbY | AL538_06215 | AL538_06225 | ATP-dependent metalloprotease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | RNA binding protein found associated to pre-50S subunit of the ribosome; putative role in ribosome assembly; necessary for optimal growth but not cell viability; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.657 |
| mreC | yhbY | AL538_07465 | AL538_06225 | Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape. | RNA binding protein found associated to pre-50S subunit of the ribosome; putative role in ribosome assembly; necessary for optimal growth but not cell viability; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.496 |
| rplK | AMF98883.1 | AL538_08675 | AL538_14760 | 50S ribosomal protein L11; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uL11 family. | Translation initiation factor IF-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.958 |