| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMF97405.1 | vfr | AL538_06375 | AL538_07990 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0231 family. | Crp/Fnr family transcriptional regulator; cAMP receptor protein; complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.657 |
| AMF98997.1 | rpoA | AL538_15355 | AL538_10950 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.688 |
| AMF98997.1 | rpoB | AL538_15355 | AL538_08655 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.708 |
| AMF98997.1 | rpoC | AL538_15355 | AL538_08650 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.673 |
| AMF98997.1 | rpoZ | AL538_15355 | AL538_10390 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.651 |
| AMF98997.1 | vfr | AL538_15355 | AL538_07990 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Crp/Fnr family transcriptional regulator; cAMP receptor protein; complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.557 |
| cpdA | cyaA | AL538_11490 | AL538_09140 | 3',5'-cyclic-nucleotide phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | Adenylate cyclase; Catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.962 |
| cpdA | vfr | AL538_11490 | AL538_07990 | 3',5'-cyclic-nucleotide phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | Crp/Fnr family transcriptional regulator; cAMP receptor protein; complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.674 |
| cyaA | cpdA | AL538_09140 | AL538_11490 | Adenylate cyclase; Catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3',5'-cyclic-nucleotide phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.962 |
| cyaA | vfr | AL538_09140 | AL538_07990 | Adenylate cyclase; Catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; Derived by automated computational analysis using gene prediction method: Protein Homology. | Crp/Fnr family transcriptional regulator; cAMP receptor protein; complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.975 |
| hfq | rpoA | AL538_08095 | AL538_10950 | RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.450 |
| hfq | rpoB | AL538_08095 | AL538_08655 | RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.496 |
| hfq | rpoD | AL538_08095 | AL538_11370 | RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | RNA polymerase subunit sigma; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.617 |
| hfq | vfr | AL538_08095 | AL538_07990 | RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Crp/Fnr family transcriptional regulator; cAMP receptor protein; complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.538 |
| rpoA | AMF98997.1 | AL538_10950 | AL538_15355 | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.688 |
| rpoA | hfq | AL538_10950 | AL538_08095 | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | RNA chaperone Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.450 |
| rpoA | rpoB | AL538_10950 | AL538_08655 | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
| rpoA | rpoC | AL538_10950 | AL538_08650 | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.998 |
| rpoA | rpoD | AL538_10950 | AL538_11370 | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | RNA polymerase subunit sigma; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.968 |
| rpoA | rpoZ | AL538_10950 | AL538_10390 | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.997 |
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