| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMF96599.1 | cpdA | AL538_02050 | AL538_11490 | Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3',5'-cyclic-nucleotide phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.927 |
| AMF96599.1 | cyaA | AL538_02050 | AL538_09140 | Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Adenylate cyclase; Catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.919 |
| AMF96599.1 | cyaB | AL538_02050 | AL538_01040 | Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Adenylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.914 |
| AMF98254.1 | cyaA | AL538_11290 | AL538_09140 | Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Adenylate cyclase; Catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.901 |
| AMF98254.1 | cyaB | AL538_11290 | AL538_01040 | Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Adenylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.900 |
| AMF98254.1 | nrdD | AL538_11290 | AL538_24435 | Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Anaerobic ribonucleoside triphosphate reductase; Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.900 |
| AMF98254.1 | ptsG | AL538_11290 | AL538_03855 | Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. | PTS glucose transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.435 |
| AMF98254.1 | pyk | AL538_11290 | AL538_03830 | Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.914 |
| AMF98254.1 | relA | AL538_11290 | AL538_06760 | Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. | (p)ppGpp synthetase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.904 |
| cpdA | AMF96599.1 | AL538_11490 | AL538_02050 | 3',5'-cyclic-nucleotide phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.927 |
| cpdA | cyaA | AL538_11490 | AL538_09140 | 3',5'-cyclic-nucleotide phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | Adenylate cyclase; Catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.962 |
| cpdA | cyaB | AL538_11490 | AL538_01040 | 3',5'-cyclic-nucleotide phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | Adenylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.914 |
| cpdA | vfr | AL538_11490 | AL538_07990 | 3',5'-cyclic-nucleotide phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | Crp/Fnr family transcriptional regulator; cAMP receptor protein; complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.674 |
| crr | cyaA | AL538_13505 | AL538_09140 | PTS glucose transporter subunit IIA; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | Adenylate cyclase; Catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.929 |
| crr | ptsG | AL538_13505 | AL538_03855 | PTS glucose transporter subunit IIA; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | PTS glucose transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
| cyaA | AMF96599.1 | AL538_09140 | AL538_02050 | Adenylate cyclase; Catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.919 |
| cyaA | AMF98254.1 | AL538_09140 | AL538_11290 | Adenylate cyclase; Catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.901 |
| cyaA | cpdA | AL538_09140 | AL538_11490 | Adenylate cyclase; Catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3',5'-cyclic-nucleotide phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.962 |
| cyaA | crr | AL538_09140 | AL538_13505 | Adenylate cyclase; Catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; Derived by automated computational analysis using gene prediction method: Protein Homology. | PTS glucose transporter subunit IIA; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.929 |
| cyaA | cyaB | AL538_09140 | AL538_01040 | Adenylate cyclase; Catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; Derived by automated computational analysis using gene prediction method: Protein Homology. | Adenylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.920 |