| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMF98689.1 | ftsL | AL538_13710 | AL538_11605 | Negative modulator of the initiation of chromosome replication; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.557 |
| AMF98689.1 | mioC | AL538_13710 | AL538_09650 | Negative modulator of the initiation of chromosome replication; Derived by automated computational analysis using gene prediction method: Protein Homology. | FMN-binding protein MioC; An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.480 |
| AMG01124.1 | mioC | AL538_26060 | AL538_09650 | Chemotaxis protein CheC; Derived by automated computational analysis using gene prediction method: Protein Homology. | FMN-binding protein MioC; An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.616 |
| cysI | mioC | AL538_07655 | AL538_09650 | Sulfite reductase subunit beta; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | FMN-binding protein MioC; An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.703 |
| dhbB | mioC | AL538_14160 | AL538_09650 | Isochorismatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | FMN-binding protein MioC; An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.771 |
| dnaA | ftsL | AL538_09690 | AL538_11605 | Chromosomal replication initiation protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. DnaA can inhibit its own gene expression. | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.524 |
| dnaA | gidA | AL538_09690 | AL538_09645 | Chromosomal replication initiation protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. DnaA can inhibit its own gene expression. | tRNA uridine(34) 5-carboxymethylaminomethyl synthesis enzyme MnmG; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 0.571 |
| dnaA | iciA | AL538_09690 | AL538_06905 | Chromosomal replication initiation protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. DnaA can inhibit its own gene expression. | Chromosome replication initiation inhibitor protein; Controls the transcription of genes involved in arginine and lysine metabolism; Belongs to the LysR transcriptional regulatory family. | 0.607 |
| dnaA | mioC | AL538_09690 | AL538_09650 | Chromosomal replication initiation protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. DnaA can inhibit its own gene expression. | FMN-binding protein MioC; An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.745 |
| dnaA | rsmG | AL538_09690 | AL538_09640 | Chromosomal replication initiation protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. DnaA can inhibit its own gene expression. | 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.728 |
| ftsL | AMF98689.1 | AL538_11605 | AL538_13710 | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | Negative modulator of the initiation of chromosome replication; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.557 |
| ftsL | dnaA | AL538_11605 | AL538_09690 | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | Chromosomal replication initiation protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. DnaA can inhibit its own gene expression. | 0.524 |
| ftsL | iciA | AL538_11605 | AL538_06905 | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | Chromosome replication initiation inhibitor protein; Controls the transcription of genes involved in arginine and lysine metabolism; Belongs to the LysR transcriptional regulatory family. | 0.449 |
| ftsL | mioC | AL538_11605 | AL538_09650 | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | FMN-binding protein MioC; An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.705 |
| ftsL | rsmG | AL538_11605 | AL538_09640 | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.432 |
| gidA | dnaA | AL538_09645 | AL538_09690 | tRNA uridine(34) 5-carboxymethylaminomethyl synthesis enzyme MnmG; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | Chromosomal replication initiation protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. DnaA can inhibit its own gene expression. | 0.571 |
| gidA | mioC | AL538_09645 | AL538_09650 | tRNA uridine(34) 5-carboxymethylaminomethyl synthesis enzyme MnmG; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | FMN-binding protein MioC; An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.828 |
| gidA | rsmG | AL538_09645 | AL538_09640 | tRNA uridine(34) 5-carboxymethylaminomethyl synthesis enzyme MnmG; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. | 0.983 |
| gidA | trmE | AL538_09645 | AL538_09655 | tRNA uridine(34) 5-carboxymethylaminomethyl synthesis enzyme MnmG; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. | tRNA uridine(34) 5-carboxymethylaminomethyl synthesis GTPase MnmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.996 |
| iciA | dnaA | AL538_06905 | AL538_09690 | Chromosome replication initiation inhibitor protein; Controls the transcription of genes involved in arginine and lysine metabolism; Belongs to the LysR transcriptional regulatory family. | Chromosomal replication initiation protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. DnaA can inhibit its own gene expression. | 0.607 |