| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMF98123.1 | rfaD | AL538_10620 | AL538_10640 | 3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | ADP-L-glycero-D-mannoheptose-6-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.950 |
| AMF98123.1 | rfaE | AL538_10620 | AL538_11470 | 3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | Bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. | 0.521 |
| AMF98123.1 | rfaF | AL538_10620 | AL538_10625 | 3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | ADP-heptose--LPS heptosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.993 |
| AMF98307.1 | rfaD | AL538_11575 | AL538_10640 | Phosphoheptose isomerase; Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | ADP-L-glycero-D-mannoheptose-6-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.816 |
| AMF98307.1 | rfaE | AL538_11575 | AL538_11470 | Phosphoheptose isomerase; Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. | 0.955 |
| AMF98307.1 | rfaF | AL538_11575 | AL538_10625 | Phosphoheptose isomerase; Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | ADP-heptose--LPS heptosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.769 |
| AMF99327.1 | rfaD | AL538_17115 | AL538_10640 | Sugar transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ADP-L-glycero-D-mannoheptose-6-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.884 |
| murQ | rfaD | AL538_12040 | AL538_10640 | N-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. | ADP-L-glycero-D-mannoheptose-6-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.858 |
| rfaD | AMF98123.1 | AL538_10640 | AL538_10620 | ADP-L-glycero-D-mannoheptose-6-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.950 |
| rfaD | AMF98307.1 | AL538_10640 | AL538_11575 | ADP-L-glycero-D-mannoheptose-6-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoheptose isomerase; Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.816 |
| rfaD | AMF99327.1 | AL538_10640 | AL538_17115 | ADP-L-glycero-D-mannoheptose-6-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sugar transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.884 |
| rfaD | murQ | AL538_10640 | AL538_12040 | ADP-L-glycero-D-mannoheptose-6-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | N-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. | 0.858 |
| rfaD | rfaE | AL538_10640 | AL538_11470 | ADP-L-glycero-D-mannoheptose-6-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. | 0.988 |
| rfaD | rfaF | AL538_10640 | AL538_10625 | ADP-L-glycero-D-mannoheptose-6-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ADP-heptose--LPS heptosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.962 |
| rfaD | rpsC | AL538_10640 | AL538_10855 | ADP-L-glycero-D-mannoheptose-6-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. | 0.835 |
| rfaD | rpsN | AL538_10640 | AL538_10890 | ADP-L-glycero-D-mannoheptose-6-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. | 0.813 |
| rfaD | rpsQ | AL538_10640 | AL538_10870 | ADP-L-glycero-D-mannoheptose-6-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. | 0.823 |
| rfaD | rpsS | AL538_10640 | AL538_10845 | ADP-L-glycero-D-mannoheptose-6-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. | 0.835 |
| rfaE | AMF98123.1 | AL538_11470 | AL538_10620 | Bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. | 3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.521 |
| rfaE | AMF98307.1 | AL538_11470 | AL538_11575 | Bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. | Phosphoheptose isomerase; Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.955 |